The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Low-density Lipoprotein Receptor
".
FunFam 43: Very low density lipoprotein receptor
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 27 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
5 | P98155 (/IPI) P98156 (/IPI) Q90W12 (/IPI) Q924X6 (/IPI) Q98931 (/IPI) |
|
Low-density lipoprotein particle receptor activity GO:0005041
Combining with a low-density lipoprotein particle and delivering the low-density lipoprotein particle into the cell via endocytosis.
|
2 | P98155 (/TAS) Q924X6 (/TAS) |
|
Lipoprotein particle receptor activity GO:0030228
Combining with a lipoprotein particle and delivering the lipoprotein particle into the cell via endocytosis. A lipoprotein particle, also known as a lipoprotein, is a clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids.
|
2 | P98165 (/IC) P98165 (/IC) |
|
Very-low-density lipoprotein particle receptor activity GO:0030229
Combining with a very-low-density lipoprotein particle and delivering the very-low-density lipoprotein into the cell via endocytosis.
|
2 | P98156 (/ISO) Q924X6 (/ISO) |
|
Very-low-density lipoprotein particle receptor activity GO:0030229
Combining with a very-low-density lipoprotein particle and delivering the very-low-density lipoprotein into the cell via endocytosis.
|
2 | P98156 (/ISS) P98166 (/ISS) |
|
Apolipoprotein binding GO:0034185
Interacting selectively and non-covalently with an apolipoprotein, the protein component of a lipoprotein complex.
|
2 | P98155 (/IDA) Q924X6 (/IDA) |
|
Apolipoprotein binding GO:0034185
Interacting selectively and non-covalently with an apolipoprotein, the protein component of a lipoprotein complex.
|
2 | P98165 (/IPI) P98165 (/IPI) |
|
Reelin receptor activity GO:0038025
Combining with the secreted glycoprotein reelin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
|
2 | P98156 (/IMP) Q924X6 (/IMP) |
|
Calcium-dependent protein binding GO:0048306
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in the presence of calcium.
|
2 | P98155 (/IPI) Q924X6 (/IPI) |
|
Amyloid-beta binding GO:0001540
Interacting selectively and non-covalently with amyloid-beta peptide/protein and/or its precursor.
|
1 | Q924X6 (/IPI) |
Showing 1 to 10 of 27 entries
There are 50 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Ventral spinal cord development GO:0021517
The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output.
|
5 | P98156 (/IEP) P98165 (/IEP) P98165 (/IEP) Q924X6 (/IEP) Q98931 (/IEP) |
|
Cerebral cortex development GO:0021987
The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon.
|
2 | D3ZE75 (/IEP) P98166 (/IEP) |
|
Very-low-density lipoprotein particle clearance GO:0034447
The process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
|
2 | P98156 (/ISS) P98166 (/ISS) |
|
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
|
2 | D3ZE75 (/IEP) P98166 (/IEP) |
|
Positive regulation of protein kinase activity GO:0045860
Any process that activates or increases the frequency, rate or extent of protein kinase activity.
|
2 | P98156 (/IGI) Q924X6 (/IGI) |
|
Dendrite morphogenesis GO:0048813
The process in which the anatomical structures of a dendrite are generated and organized.
|
2 | P98156 (/IMP) Q924X6 (/IMP) |
|
Positive regulation of dendrite development GO:1900006
Any process that activates or increases the frequency, rate or extent of dendrite development.
|
2 | P98156 (/IGI) Q924X6 (/IGI) |
|
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
|
1 | P98166 (/IEP) |
|
Endocytosis GO:0006897
A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
|
1 | Q924X6 (/ISO) |
|
Endocytosis GO:0006897
A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
|
1 | Q924X6 (/ISS) |
Showing 1 to 10 of 50 entries
There are 27 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
3 | D3ZE75 (/IDA) P98155 (/IDA) Q90W12 (/IDA) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
2 | P98156 (/IDA) Q924X6 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | P98155 (/TAS) Q924X6 (/TAS) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
2 | P98166 (/IDA) Q924X6 (/IDA) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
2 | P98156 (/ISO) Q924X6 (/ISO) |
|
Receptor complex GO:0043235
Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
2 | P98156 (/ISO) Q924X6 (/ISO) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | P98166 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | P98156 (/ISO) |
|
Lysosomal membrane GO:0005765
The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.
|
1 | P98155 (/TAS) |
|
Microtubule associated complex GO:0005875
Any multimeric complex connected to a microtubule.
|
1 | D3ZE75 (/IDA) |
Showing 1 to 10 of 27 entries
