The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Low-density Lipoprotein Receptor
".
FunFam 220: Lipophorin receptor 2, isoform A
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Lipoprotein particle binding GO:0071813
Interacting selectively and non-covalently with a lipoprotein particle. A lipoprotein particle, also known as a lipoprotein, is a clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids.
|
8 | A0A0B4KGZ9 (/IPI) A0A0B4KH38 (/IPI) A8JRC4 (/IPI) A8JRC7 (/IPI) Q7YTZ6 (/IPI) Q7YU01 (/IPI) Q86B77 (/IPI) Q9VBN2 (/IPI) |
|
Low-density lipoprotein particle receptor activity GO:0005041
Combining with a low-density lipoprotein particle and delivering the low-density lipoprotein particle into the cell via endocytosis.
|
1 | E9QGD4 (/IMP) |
There are 4 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Positive regulation of lipid transport GO:0032370
Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
8 | A0A0B4KGZ9 (/IMP) A0A0B4KH38 (/IMP) A8JRC4 (/IMP) A8JRC7 (/IMP) Q7YTZ6 (/IMP) Q7YU01 (/IMP) Q86B77 (/IMP) Q9VBN2 (/IMP) |
|
Cholesterol homeostasis GO:0042632
Any process involved in the maintenance of an internal steady state of cholesterol within an organism or cell.
|
1 | E9QGD4 (/IMP) |
|
Cellular response to lipopolysaccharide GO:0071222
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
|
1 | E9QGD4 (/IMP) |
|
Receptor-mediated endocytosis involved in cholesterol transport GO:0090118
A receptor-mediated endocytosis process involved in intracellular cholesterol transport.
|
1 | E9QGD4 (/IMP) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
8 | A0A0B4KGZ9 (/IDA) A0A0B4KH38 (/IDA) A8JRC4 (/IDA) A8JRC7 (/IDA) Q7YTZ6 (/IDA) Q7YU01 (/IDA) Q86B77 (/IDA) Q9VBN2 (/IDA) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
1 | Q99087 (/ISS) |
