The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Low-density Lipoprotein Receptor
".
FunFam 187: Tequila, isoform G
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Serine-type endopeptidase activity GO:0004252
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
|
7 | E1JI93 (/ISM) Q8IQB8 (/ISM) Q960G6 (/ISM) Q9BI19 (/ISM) Q9U1I2 (/ISM) Q9U1I3 (/ISM) Q9VSU2 (/ISM) |
|
Low-density lipoprotein particle receptor activity GO:0005041
Combining with a low-density lipoprotein particle and delivering the low-density lipoprotein particle into the cell via endocytosis.
|
1 | O44191 (/IDA) |
|
Cargo receptor activity GO:0038024
Binding specifically to a substance (cargo) to deliver it to a transport vesicle. Cargo receptors span a membrane (either the plasma membrane or a vesicle membrane), binding simultaneously to cargo molecules and coat adaptors, to efficiently recruit soluble proteins to nascent vesicles.
|
1 | A8JRD0 (/IMP) |
There are 10 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
|
7 | E1JI93 (/ISM) Q8IQB8 (/ISM) Q960G6 (/ISM) Q9BI19 (/ISM) Q9U1I2 (/ISM) Q9U1I3 (/ISM) Q9VSU2 (/ISM) |
|
Short-term memory GO:0007614
The memory process that deals with the storage, retrieval and modification of information received a short time (up to about 30 minutes) ago. This type of memory is typically dependent on direct, transient effects of second messenger activation.
|
7 | E1JI93 (/IDA) Q8IQB8 (/IDA) Q960G6 (/IDA) Q9BI19 (/IDA) Q9U1I2 (/IDA) Q9U1I3 (/IDA) Q9VSU2 (/IDA) |
|
Long-term memory GO:0007616
The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation.
|
7 | E1JI93 (/IMP) Q8IQB8 (/IMP) Q960G6 (/IMP) Q9BI19 (/IMP) Q9U1I2 (/IMP) Q9U1I3 (/IMP) Q9VSU2 (/IMP) |
|
Receptor-mediated endocytosis GO:0006898
An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.
|
1 | A8JRD0 (/IEP) |
|
Receptor-mediated endocytosis GO:0006898
An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.
|
1 | A8JRD0 (/IMP) |
|
Embryo development ending in birth or egg hatching GO:0009792
The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
|
1 | O44191 (/IMP) |
|
Ovulation GO:0030728
The release of a mature ovum/oocyte from an ovary.
|
1 | O44191 (/IMP) |
|
Positive regulation of insulin secretion GO:0032024
Any process that activates or increases the frequency, rate or extent of the regulated release of insulin.
|
1 | Q9VSU2 (/IMP) |
|
Glucose homeostasis GO:0042593
Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
|
1 | Q9VSU2 (/IMP) |
|
Oocyte development GO:0048599
The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
|
1 | O44191 (/IMP) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | O44191 (/IDA) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | O44191 (/IDA) |
|
Endosome membrane GO:0010008
The lipid bilayer surrounding an endosome.
|
1 | O44191 (/IDA) |
|
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
|
1 | O44191 (/IDA) |
