The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Tat domain
".
FunFam 1: Protein Tat
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | P04326 (/IPI) P04608 (/IPI) P04608 (/IPI) |
|
RNA-binding transcription regulator activity GO:0001070
Interacting selectively and non-covalently with an RNA sequence in order to modulate transcription. This function is known to occur in phages and viruses, for example the lambda N and the HIV tat proteins are necessary to allow RNA polymerase to read through terminator sequences.
|
2 | P04608 (/TAS) P04608 (/TAS) |
|
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
|
2 | P04608 (/IPI) P04608 (/IPI) |
|
Cyclin binding GO:0030332
Interacting selectively and non-covalently with cyclins, proteins whose levels in a cell varies markedly during the cell cycle, rising steadily until mitosis, then falling abruptly to zero. As cyclins reach a threshold level, they are thought to drive cells into G2 phase and thus to mitosis.
|
2 | P04608 (/IPI) P04608 (/IPI) |
|
Actinin binding GO:0042805
Interacting selectively and non-covalently with actinin, any member of a family of proteins that crosslink F-actin.
|
2 | P04608 (/IPI) P04608 (/IPI) |
|
Trans-activation response element binding GO:1990970
Interacting selectively and non-covalently with a trans-activation response (TAR) element, a hairpin RNA structure located at the 5' end of all HIV-1 transcripts, and which is required for trans-activation of a viral promoter.
|
2 | P04608 (/IPI) P04608 (/IPI) |
There are 11 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of peptidyl-threonine phosphorylation GO:0010801
Any process that decreases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
|
2 | P04608 (/IMP) P04608 (/IMP) |
|
Positive regulation of transcription elongation from RNA polymerase II promoter GO:0032968
Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
|
2 | P04608 (/IDA) P04608 (/IDA) |
|
Modulation by virus of host chromatin organization GO:0039525
Any process in which a virus effects a change in the organization of chromatin in the host.
|
2 | P04608 (/IDA) P04608 (/IDA) |
|
Positive regulation of viral transcription GO:0050434
Any process that activates or increases the frequency, rate or extent of viral transcription.
|
2 | P04608 (/IDA) P04608 (/IDA) |
|
Positive regulation of viral transcription GO:0050434
Any process that activates or increases the frequency, rate or extent of viral transcription.
|
2 | P04608 (/IMP) P04608 (/IMP) |
|
Positive regulation of viral transcription GO:0050434
Any process that activates or increases the frequency, rate or extent of viral transcription.
|
2 | P04608 (/TAS) P04608 (/TAS) |
|
Positive regulation of NF-kappaB transcription factor activity GO:0051092
Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB.
|
2 | P04610 (/IDA) P04610 (/IDA) |
|
Modulation of transcription in other organism involved in symbiotic interaction GO:0052312
Any process in which an organism modulates the frequency, rate or extent of transcription in a second organism, where the two organisms are in a symbiotic interaction.
|
2 | P04610 (/IDA) P04610 (/IDA) |
|
Membrane hyperpolarization GO:0060081
The process in which membrane potential increases with respect to its steady-state potential, usually from negative potential to a more negative potential. For example, during the repolarization phase of an action potential the membrane potential often becomes more negative or hyperpolarized before returning to the steady-state resting potential.
|
2 | P04610 (/IDA) P04610 (/IDA) |
|
Positive regulation of protein localization to nucleus GO:1900182
Any process that activates or increases the frequency, rate or extent of protein localization to nucleus.
|
2 | P04610 (/IDA) P04610 (/IDA) |
|
Negative regulation of cellular respiration GO:1901856
Any process that stops, prevents or reduces the frequency, rate or extent of cellular respiration.
|
2 | P04610 (/IDA) P04610 (/IDA) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Host cell nucleus GO:0042025
A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.
|
2 | P04608 (/IC) P04608 (/IC) |
|
Host cell nucleus GO:0042025
A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.
|
2 | P04608 (/IDA) P04608 (/IDA) |
