The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
GPCR, family 2, extracellular hormone receptor domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1Parathyroid hormone/parathyroid hormone-related peptide receptorGlucagon receptorCalcitonin gene-related peptide type 1 receptorCalcitonin receptorGlucagon like peptide 1 receptorGrowth hormone-releasing hormone receptor 2Gastric inhibitory polypeptide receptorSC:2Adhesion G protein-coupled receptor L2Adhesion G protein-coupled receptor B2Corticotropin-releasing factor receptor 1Putative cadherin EGF LAG seven-pass G-type receptor 2Adhesion G protein-coupled receptor L3corticotropin-releasing factor receptor 2 isoform X2pituitary adenylate cyclase-activating polypeptide type I receptorCadherin EGF LAG seven-pass G-type receptor 3Vasoactive intestinal polypeptide receptor 2Vasoactive intestinal peptide receptor 1Glucagon like peptide 2 receptorSecretin receptorAdhesion G protein-coupled receptor F3Cadherin EGF LAG seven-pass G-type receptorAdenylate cyclase-activating polypeptide 1a (pituitary) receptor type IUncharacterized protein, isoform Blatrophilin Cirl isoform X1Corticotropin releasing hormone receptor 2Blast:Peroxidasin homologPituitary adenylate cyclase-activating polypeptide type I receptor isoform AFlaMIngo (Cadherin plus 7TM domain) homologPDF receptor isoform X3Vasoactive intestinal polypeptide receptorGrowth hormone-releasing hormone receptor aCadherin EGF LAG seven-pass G-type receptor 3LOC100145780 proteinDiuretic hormone 31 receptor, isoform BGlucagon receptor aAdhesion G protein-coupled receptor A2Latrophilin-like protein 1Vasoactive intestinal peptide receptor 2Corticotropin-releasing hormone receptor 2Hector, isoform APutative diuretic hormone 44 receptorParathyroid hormone receptor-like protein bf98CParathyroid hormone 1 receptorUncharacterized proteinCalcitonin gene-related peptide type 1 receptor-like ProteinDiuretic hormone receptor precursor, putativeParathyroid hormone receptor like 2Uncharacterized proteinSEcretin/class B GPCRGlucagon-like peptide 1 receptorGlucagon receptor aSecretin receptorPDF receptor-like ProteinAdenylate cyclase-activating polypeptide 1 (pituitary) receptor type IUncharacterized proteinPutative g protein-coupled receptorLatrophilin-like protein LAT-2Uncharacterized proteinadhesion G protein-coupled receptor L3Adhesion G protein-coupled receptor B3Adhesion G protein-coupled receptor L1Uncharacterized proteinContactin-6Adhesion G protein-coupled receptor L2Adhesion G protein-coupled receptor L3Receptor-type tyrosine-protein phosphatase FAdhesion G protein-coupled receptor L3Gastric inhibitory polypeptide receptorC1A receptor, putativeUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinCalcitonin receptor, putativeUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized protein (Fragment)C1A receptor, putativePredicted proteinPituitary adenylate cyclase-activating polypeptide type I receptorUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized protein
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FunFam 25: Corticotropin releasing hormone receptor 2

There are 0 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

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