The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
EGF-type module
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: Basement membrane proteoglycan

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Structural molecule activity GO:0005198
The action of a molecule that contributes to the structural integrity of a complex or its assembly within or outside a cell.
8 G5EEI5 (/ISS) H9G348 (/ISS) H9G349 (/ISS) H9G350 (/ISS) H9G351 (/ISS) H9G352 (/ISS) H9G353 (/ISS) H9G354 (/ISS)
Extracellular matrix structural constituent GO:0005201
The action of a molecule that contributes to the structural integrity of the extracellular matrix.
1 Q06561 (/IMP)

There are 16 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Muscle organ development GO:0007517
The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.
9 G5EEI5 (/IMP) H9G348 (/IMP) H9G349 (/IMP) H9G350 (/IMP) H9G351 (/IMP) H9G352 (/IMP) H9G353 (/IMP) H9G354 (/IMP) Q06561 (/IMP)
Fibroblast growth factor receptor signaling pathway GO:0008543
The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands.
9 G5EEI5 (/IGI) H9G348 (/IGI) H9G349 (/IGI) H9G350 (/IGI) H9G351 (/IGI) H9G352 (/IGI) H9G353 (/IGI) H9G354 (/IGI) Q06561 (/IGI)
Embryo development ending in birth or egg hatching GO:0009792
The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
9 G5EEI5 (/IGI) H9G348 (/IGI) H9G349 (/IGI) H9G350 (/IGI) H9G351 (/IGI) H9G352 (/IGI) H9G353 (/IGI) H9G354 (/IGI) Q06561 (/IGI)
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
9 G5EEI5 (/IGI) H9G348 (/IGI) H9G349 (/IGI) H9G350 (/IGI) H9G351 (/IGI) H9G352 (/IGI) H9G353 (/IGI) H9G354 (/IGI) Q06561 (/IGI)
Hemidesmosome assembly GO:0031581
Assembly of hemidesmosomes, integrin-containing protein complexes that bind to laminin in the basal lamina. Hemidesmosomes form the contact between the basal surface of epithelial cells and the underlying basal lamina.
9 G5EEI5 (/IGI) H9G348 (/IGI) H9G349 (/IGI) H9G350 (/IGI) H9G351 (/IGI) H9G352 (/IGI) H9G353 (/IGI) H9G354 (/IGI) Q06561 (/IGI)
Locomotion GO:0040011
Self-propelled movement of a cell or organism from one location to another.
9 G5EEI5 (/IMP) H9G348 (/IMP) H9G349 (/IMP) H9G350 (/IMP) H9G351 (/IMP) H9G352 (/IMP) H9G353 (/IMP) H9G354 (/IMP) Q06561 (/IMP)
Positive regulation of locomotion GO:0040017
Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism.
9 G5EEI5 (/IMP) H9G348 (/IMP) H9G349 (/IMP) H9G350 (/IMP) H9G351 (/IMP) H9G352 (/IMP) H9G353 (/IMP) H9G354 (/IMP) Q06561 (/IMP)
Muscle organ morphogenesis GO:0048644
The process in which the anatomical structures of muscle are generated and organized.
9 G5EEI5 (/IGI) H9G348 (/IGI) H9G349 (/IGI) H9G350 (/IGI) H9G351 (/IGI) H9G352 (/IGI) H9G353 (/IGI) H9G354 (/IGI) Q06561 (/IGI)
Nematode larval development GO:0002119
The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.
1 Q06561 (/IMP)
Mitochondrion organization GO:0007005
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
1 Q06561 (/IMP)
Myofibril assembly GO:0030239
Formation of myofibrils, the repeating units of striated muscle.
1 Q06561 (/IEP)
Muscle cell cellular homeostasis GO:0046716
The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state.
1 Q06561 (/IMP)
Positive regulation of ovulation GO:0060279
Any process that activates or increases the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.
1 Q06561 (/IMP)
Positive regulation of sarcomere organization GO:0060298
Any process that increases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
1 Q06561 (/IMP)
Pharynx development GO:0060465
The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth.
1 Q06561 (/IMP)
Pharyngeal gland morphogenesis GO:1905905
The developmental process by which a pharyngeal gland is generated and organized.
1 Q06561 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Basement membrane GO:0005604
A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
9 G5EEI5 (/IDA) H9G348 (/IDA) H9G349 (/IDA) H9G350 (/IDA) H9G351 (/IDA) H9G352 (/IDA) H9G353 (/IDA) H9G354 (/IDA) Q06561 (/IDA)
Extracellular matrix GO:0031012
A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.
1 Q06561 (/IDA)
Striated muscle dense body GO:0055120
A vinculin-containing myofibril attachment structure of striated muscle that connects sarcomeres to the extracellular matrix. In nematode body wall muscle, the dense body performs the dual role of Z-disk and costamere.
1 Q06561 (/IDA)
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