The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1Leucine--tRNA ligaseLeucine--tRNA ligaseLeucine--tRNA ligaseLeucine--tRNA ligase, cytoplasmicIsoleucine--tRNA ligaseValine--tRNA ligaseValine--tRNA ligaseValine--tRNA ligase, mitochondrialIsoleucine--tRNA ligaseValine--tRNA ligase, mitochondrialValine--tRNA ligase, mitochondrialIsoleucyl-tRNA synthetase 2, mitochondrialValine--tRNA ligaseValine--tRNA ligaseIsoleucine--tRNA ligase, chloroplastic/mitochondrialvaline--tRNA ligase, mitochondrialValine--tRNA ligaseIsoleucine--tRNA ligaseValine--tRNA ligaseIsoleucine--tRNA ligase, cytoplasmicLeucine--tRNA ligase, putativeValine--tRNA ligaseIsoleucine--tRNA ligaseIsoleucine--tRNA ligase, putativeValine--tRNA ligase, chloroplastic/mitochondrial 2 isoform X2Leucyl-tRNA synthetaseIsoleucyl-tRNA synthetase 2, mitochondrialValine--tRNA ligaseMitochondrial isoleucyl-tRNA synthetasevaline--tRNA ligasevaline--tRNA ligase, chloroplastic/mitochondrial 2 isoform X3Isoleucine--tRNA ligaseIsoleucyl-tRNA synthetase, putativeLeucine--tRNA ligase, mitochondrialIsoleucyl-tRNA synthetaseIsoleucyl-tRNA synthetaseIsoleucyl-tRNA synthetase (Mitochondrial)Isoleucyl-tRNA synthetaseIsoleucine--tRNA ligaseValine--tRNA ligaseIsoleucine--tRNA ligaseValine--tRNA ligaseIsoleucine-tRNA ligaseIsoleucine--tRNA ligaseLeucine--tRNA ligaseIsoleucine--tRNA ligaseLeucine--tRNA ligase, putativeLeucine--tRNA ligaseOs01g0120300 proteinUncharacterized proteinLeucine--tRNA ligaseValine--tRNA ligaseValine--tRNA ligaseIsoleucine--tRNA ligaseValyl Amino-acyl tRNA SynthetaseIsoleucine--tRNA ligase, cytoplasmicValyl tRNA SynthetasePutative isoleucine-tRNA ligaseValine--tRNA ligaseUncharacterized proteinIsoleucine--tRNA ligase, mitochondrialIsoleucine--tRNA ligase, cytoplasmic-likeUncharacterized proteinUncharacterized proteinUncharacterized proteinLeucyl-tRNA synthetase aUncharacterized proteinOs05g0241100 proteinUncharacterized proteinUncharacterized proteinIsoleucyl tRNA synthetase, putativeLeucyl-tRNA synthetase bATP binding / aminoacyl-tRNA ligase/ nucleotide binding proteinLeucyl-tRNA synthetase bValyl-tRNA synthetaseATP binding / aminoacyl-tRNA ligase/ nucleotide binding proteinPredicted protein
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FunFam 28: Valine--tRNA ligase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC TermAnnotationsEvidence
Valine--tRNA ligase. [EC: 6.1.1.9]
ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val).
    45 A0A0H3Q2Q1 A0A0H3Q2Q1 A0A0H3Q2Q1 A0A0H3Q2Q1 A0A0H3Q2Q1 A0A0H3Q2Q1 A0A0H6CU64 A0A0H6CU64 A0A0H6CU64 A0A0H6CU64
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