The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Plus-3 domain
".
FunFam 1: RNA polymerase-associated protein RTF1 homolog
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Single-stranded DNA binding GO:0003697
Interacting selectively and non-covalently with single-stranded DNA.
|
7 | Q92541 (/IDA) Q92541 (/IDA) Q92541 (/IDA) Q92541 (/IDA) Q92541 (/IDA) Q92541 (/IDA) Q92541 (/IDA) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
7 | Q92541 (/HDA) Q92541 (/HDA) Q92541 (/HDA) Q92541 (/HDA) Q92541 (/HDA) Q92541 (/HDA) Q92541 (/HDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
7 | Q92541 (/IPI) Q92541 (/IPI) Q92541 (/IPI) Q92541 (/IPI) Q92541 (/IPI) Q92541 (/IPI) Q92541 (/IPI) |
|
Single-stranded DNA binding GO:0003697
Interacting selectively and non-covalently with single-stranded DNA.
|
2 | A2AQ19 (/ISS) Q5RAD5 (/ISS) |
|
Histone methyltransferase activity (H3-K4 specific) GO:0042800
Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 4) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 4). This reaction is the addition of a methyl group onto lysine at position 4 of the histone H3 protein.
|
2 | Q9W261 (/IMP) Q9W261 (/IMP) |
|
Single-stranded DNA binding GO:0003697
Interacting selectively and non-covalently with single-stranded DNA.
|
1 | A2AQ19 (/ISO) |
Showing 1 to 6 of 6 entries
There are 30 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
8 | Q5RAD5 (/ISS) Q92541 (/ISS) Q92541 (/ISS) Q92541 (/ISS) Q92541 (/ISS) Q92541 (/ISS) Q92541 (/ISS) Q92541 (/ISS) |
|
Endodermal cell fate commitment GO:0001711
The cell differentiation process that results in commitment of a cell to become part of the endoderm.
|
8 | Q5RAD5 (/ISS) Q92541 (/ISS) Q92541 (/ISS) Q92541 (/ISS) Q92541 (/ISS) Q92541 (/ISS) Q92541 (/ISS) Q92541 (/ISS) |
|
Transcription by RNA polymerase II GO:0006366
The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
|
7 | Q92541 (/TAS) Q92541 (/TAS) Q92541 (/TAS) Q92541 (/TAS) Q92541 (/TAS) Q92541 (/TAS) Q92541 (/TAS) |
|
Transcription elongation from RNA polymerase II promoter GO:0006368
The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II.
|
7 | Q92541 (/TAS) Q92541 (/TAS) Q92541 (/TAS) Q92541 (/TAS) Q92541 (/TAS) Q92541 (/TAS) Q92541 (/TAS) |
|
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
7 | Q92541 (/TAS) Q92541 (/TAS) Q92541 (/TAS) Q92541 (/TAS) Q92541 (/TAS) Q92541 (/TAS) Q92541 (/TAS) |
|
Stem cell population maintenance GO:0019827
The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types.
|
7 | Q92541 (/IDA) Q92541 (/IDA) Q92541 (/IDA) Q92541 (/IDA) Q92541 (/IDA) Q92541 (/IDA) Q92541 (/IDA) |
|
Positive regulation of transcription elongation from RNA polymerase II promoter GO:0032968
Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
|
7 | Q92541 (/IDA) Q92541 (/IDA) Q92541 (/IDA) Q92541 (/IDA) Q92541 (/IDA) Q92541 (/IDA) Q92541 (/IDA) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
7 | Q92541 (/IDA) Q92541 (/IDA) Q92541 (/IDA) Q92541 (/IDA) Q92541 (/IDA) Q92541 (/IDA) Q92541 (/IDA) |
|
Positive regulation of histone H3-K4 methylation GO:0051571
Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3.
|
3 | A2AQ19 (/IMP) Q9W261 (/IMP) Q9W261 (/IMP) |
|
Somitogenesis GO:0001756
The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
|
2 | A3KDM2 (/IGI) G1K2X4 (/IGI) |
Showing 1 to 10 of 30 entries
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
7 | Q92541 (/TAS) Q92541 (/TAS) Q92541 (/TAS) Q92541 (/TAS) Q92541 (/TAS) Q92541 (/TAS) Q92541 (/TAS) |
|
Cdc73/Paf1 complex GO:0016593
A multiprotein complex that associates with RNA polymerase II and general RNA polymerase II transcription factor complexes and may be involved in both transcriptional initiation and elongation. In Saccharomyces the complex contains Paf1p, Cdc73p, Ctr9p, Rtf1p, and Leo1p.
|
7 | Q92541 (/IDA) Q92541 (/IDA) Q92541 (/IDA) Q92541 (/IDA) Q92541 (/IDA) Q92541 (/IDA) Q92541 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
4 | A3KDM2 (/IDA) G1K2X4 (/IDA) Q9W261 (/IDA) Q9W261 (/IDA) |
|
Cdc73/Paf1 complex GO:0016593
A multiprotein complex that associates with RNA polymerase II and general RNA polymerase II transcription factor complexes and may be involved in both transcriptional initiation and elongation. In Saccharomyces the complex contains Paf1p, Cdc73p, Ctr9p, Rtf1p, and Leo1p.
|
2 | A2AQ19 (/ISS) Q5RAD5 (/ISS) |
|
Transcriptionally active chromatin GO:0035327
The ordered and organized complex of DNA and protein that forms regions of the chromosome that are being actively transcribed.
|
2 | Q9W261 (/IDA) Q9W261 (/IDA) |
|
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
1 | A2AQ19 (/IDA) |
|
Cdc73/Paf1 complex GO:0016593
A multiprotein complex that associates with RNA polymerase II and general RNA polymerase II transcription factor complexes and may be involved in both transcriptional initiation and elongation. In Saccharomyces the complex contains Paf1p, Cdc73p, Ctr9p, Rtf1p, and Leo1p.
|
1 | A2AQ19 (/IPI) |
|
Cdc73/Paf1 complex GO:0016593
A multiprotein complex that associates with RNA polymerase II and general RNA polymerase II transcription factor complexes and may be involved in both transcriptional initiation and elongation. In Saccharomyces the complex contains Paf1p, Cdc73p, Ctr9p, Rtf1p, and Leo1p.
|
1 | A2AQ19 (/ISO) |
Showing 1 to 8 of 8 entries
