The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
2-enoyl-CoA Hydratase; Chain A, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: 1,4-dihydroxy-2-naphthoyl-CoA synthase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
1,4-dihydroxy-2-naphthoyl-CoA synthase activity GO:0008935
Catalysis of the reaction: 4-(2-carboxyphenyl)-4-oxobutanoyl-CoA = 1,4-dihydroxy-2-napthoyl-CoA + H2O.
140 A0QRD3 (/IDA) A0QRD3 (/IDA) A0QRD3 (/IDA) P0ABU0 (/IDA) P0ABU0 (/IDA) P0ABU0 (/IDA) P0ABU0 (/IDA) P0ABU0 (/IDA) P0ABU0 (/IDA) P0ABU0 (/IDA)
(130 more)
Bicarbonate binding GO:0071890
Interacting selectively and non-covalently with bicarbonate (CHO3-) ions.
130 P0ABU0 (/IDA) P0ABU0 (/IDA) P0ABU0 (/IDA) P0ABU0 (/IDA) P0ABU0 (/IDA) P0ABU0 (/IDA) P0ABU0 (/IDA) P0ABU0 (/IDA) P0ABU0 (/IDA) P0ABU0 (/IDA)
(120 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
115 P0ABU0 (/IPI) P0ABU0 (/IPI) P0ABU0 (/IPI) P0ABU0 (/IPI) P0ABU0 (/IPI) P0ABU0 (/IPI) P0ABU0 (/IPI) P0ABU0 (/IPI) P0ABU0 (/IPI) P0ABU0 (/IPI)
(105 more)
1,4-dihydroxy-2-naphthoyl-CoA synthase activity GO:0008935
Catalysis of the reaction: 4-(2-carboxyphenyl)-4-oxobutanoyl-CoA = 1,4-dihydroxy-2-napthoyl-CoA + H2O.
8 A0QRD3 (/ISS) A0QRD3 (/ISS) A0QRD3 (/ISS) Q8E8C7 (/ISS) Q9KQM5 (/ISS) Q9KQM5 (/ISS) Q9KQM5 (/ISS) Q9KQM5 (/ISS)
1,4-dihydroxy-2-naphthoyl-CoA synthase activity GO:0008935
Catalysis of the reaction: 4-(2-carboxyphenyl)-4-oxobutanoyl-CoA = 1,4-dihydroxy-2-napthoyl-CoA + H2O.
1 Q8GYN9 (/TAS)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Menaquinone biosynthetic process GO:0009234
The chemical reactions and pathways resulting in the formation of any of the menaquinones. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones that have vitamin K activity and are known as vitamin K2.
115 P0ABU0 (/IMP) P0ABU0 (/IMP) P0ABU0 (/IMP) P0ABU0 (/IMP) P0ABU0 (/IMP) P0ABU0 (/IMP) P0ABU0 (/IMP) P0ABU0 (/IMP) P0ABU0 (/IMP) P0ABU0 (/IMP)
(105 more)
Menaquinone biosynthetic process GO:0009234
The chemical reactions and pathways resulting in the formation of any of the menaquinones. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones that have vitamin K activity and are known as vitamin K2.
15 P23966 (/IGC) P23966 (/IGC) P23966 (/IGC) P23966 (/IGC) P23966 (/IGC) P23966 (/IGC) P23966 (/IGC) P23966 (/IGC) P23966 (/IGC) P23966 (/IGC)
(5 more)
Menaquinone biosynthetic process GO:0009234
The chemical reactions and pathways resulting in the formation of any of the menaquinones. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones that have vitamin K activity and are known as vitamin K2.
8 A0QRD3 (/ISS) A0QRD3 (/ISS) A0QRD3 (/ISS) Q8E8C7 (/ISS) Q9KQM5 (/ISS) Q9KQM5 (/ISS) Q9KQM5 (/ISS) Q9KQM5 (/ISS)
Menaquinone biosynthetic process GO:0009234
The chemical reactions and pathways resulting in the formation of any of the menaquinones. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones that have vitamin K activity and are known as vitamin K2.
7 P9WNP5 (/IDA) P9WNP5 (/IDA) P9WNP5 (/IDA) P9WNP5 (/IDA) P9WNP5 (/IDA) P9WNP5 (/IDA) P9WNP5 (/IDA)
Protein hexamerization GO:0034214
The formation of a protein hexamer, a macromolecular structure consisting of six noncovalently associated identical or nonidentical subunits.
7 P9WNP5 (/IDA) P9WNP5 (/IDA) P9WNP5 (/IDA) P9WNP5 (/IDA) P9WNP5 (/IDA) P9WNP5 (/IDA) P9WNP5 (/IDA)
Phylloquinone biosynthetic process GO:0042372
The chemical reactions and pathways resulting in the formation of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants.
1 Q8GYN9 (/TAS)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
115 P0ABU0 (/IDA) P0ABU0 (/IDA) P0ABU0 (/IDA) P0ABU0 (/IDA) P0ABU0 (/IDA) P0ABU0 (/IDA) P0ABU0 (/IDA) P0ABU0 (/IDA) P0ABU0 (/IDA) P0ABU0 (/IDA)
(105 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
7 P9WNP5 (/HDA) P9WNP5 (/HDA) P9WNP5 (/HDA) P9WNP5 (/HDA) P9WNP5 (/HDA) P9WNP5 (/HDA) P9WNP5 (/HDA)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
1 Q8GYN9 (/IDA)
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