The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"endopeptidase domain like (from Nostoc punctiforme)
".
FunFam 4: Bifunctional glutathionylspermidine synthetase/ami...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
65 |
P0AES0 (/IPI)
P0AES0 (/IPI)
P0AES0 (/IPI)
P0AES0 (/IPI)
P0AES0 (/IPI)
P0AES0 (/IPI)
P0AES0 (/IPI)
P0AES0 (/IPI)
P0AES0 (/IPI)
P0AES0 (/IPI)
(55 more) |
|
Glutathionylspermidine amidase activity GO:0008884
Catalysis of the reaction: N1-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + H2O = gamma-L-glutamyl-L-cysteinyl-glycine + spermidine.
|
65 |
P0AES0 (/IDA)
P0AES0 (/IDA)
P0AES0 (/IDA)
P0AES0 (/IDA)
P0AES0 (/IDA)
P0AES0 (/IDA)
P0AES0 (/IDA)
P0AES0 (/IDA)
P0AES0 (/IDA)
P0AES0 (/IDA)
(55 more) |
|
Glutathionylspermidine synthase activity GO:0008885
Catalysis of the reaction: gamma-L-glutamyl-L-cysteinyl-glycine + spermidine + ATP = N1-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + ADP + phosphate.
|
65 |
P0AES0 (/IDA)
P0AES0 (/IDA)
P0AES0 (/IDA)
P0AES0 (/IDA)
P0AES0 (/IDA)
P0AES0 (/IDA)
P0AES0 (/IDA)
P0AES0 (/IDA)
P0AES0 (/IDA)
P0AES0 (/IDA)
(55 more) |
|
Glutathionylspermidine synthase activity GO:0008885
Catalysis of the reaction: gamma-L-glutamyl-L-cysteinyl-glycine + spermidine + ATP = N1-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + ADP + phosphate.
|
1 | Q384E7 (/ISA) |
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cellular biogenic amine metabolic process GO:0006576
The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.
|
1 | Q384E7 (/ISA) |
|
Trypanothione biosynthetic process GO:0019342
The chemical reactions and pathways resulting in the formation of trypanothione (N1,N6,-bis(glutathionyl)spermidine) in two steps from glutathione and spermidine via an N1- or N8-glutathionylspermidine intermediate. Trypanothione appears to be an essential redox intermediate in intracellular thiol redox regulation. It also plays a role in protecting against oxidative stress.
|
1 | Q57XE8 (/ISA) |
|
Trypanothione metabolic process GO:0046206
The chemical reactions and pathways involving trypanothione (N1,N6,-bis(glutathionyl)spermidine), an essential redox intermediate in intracellular thiol redox regulation which also plays a role in protecting against oxidative stress.
|
1 | Q57XE8 (/ISA) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
65 |
P0AES0 (/IDA)
P0AES0 (/IDA)
P0AES0 (/IDA)
P0AES0 (/IDA)
P0AES0 (/IDA)
P0AES0 (/IDA)
P0AES0 (/IDA)
P0AES0 (/IDA)
P0AES0 (/IDA)
P0AES0 (/IDA)
(55 more) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q384E7 (/IDA) Q586Y2 (/IDA) |
