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CATH Superfamily 3.90.1660.10

CofE-like domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
CofE-like domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Coenzyme F420:L-glutamate ligase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Coenzyme F420-1:gamma-L-glutamate ligase. [EC: 6.3.2.34]
GTP + coenzyme F420-1 + L-glutamate = GDP + phosphate + coenzyme gamma- F420-2.
  • This protein catalyzes the successive addition of two glutamate residues to cofactor F420 by two distinct and independent reactions.
  • In the first reaction (EC 6.3.2.31) the enzyme attaches a glutamate via its alpha-amine group to F420-0.
  • In the second reaction, which is described here, the enzyme catalyzes the addition of a second L-glutamate residue to the gamma-carboxyl of the first glutamate.
 1 Q9KZK8
Coenzyme F420-0:L-glutamate ligase. [EC: 6.3.2.31]
GTP + coenzyme F420-0 + L-glutamate = GDP + phosphate + coenzyme F420-1.
  • This protein catalyzes the successive addition of two glutamate residues to cofactor F420 by two distinct and independent reactions.
  • In the reaction described here the enzyme attaches a glutamate via its alpha-amine group to F420-0.
  • In the second reaction (EC 6.3.2.34) it catalyzes the addition of a second L-glutamate residue to the gamma-carboxyl of the first glutamate.
 1 Q9KZK8
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