The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
set domain protein methyltransferase, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1histone-lysine N-methyltransferase setd3 isoform X1N-lysine methyltransferase SETD6Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplasticSET domain-containing protein 4 isoform X1Rubisco methyltransferase family proteinRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplasticRibosomal lysine N-methyltransferase 4SET domain-containing proteinHistone-lysine N-methyltransferase setd3Protein PLASTID TRANSCRIPTIONALLY ACTIVE 14Transcription factor, E2F and DP-relatedProtein SET DOMAIN GROUP 40N-lysine methyltransferase SETD6SET domain-containing proteinRibosomal lysine N-methyltransferase 4Lysine methyltransferaseYBR030W-like proteinN-lysine methyltransferase SETD6 isoform X2N-lysine methyltransferaseHypothetical_protein_-_conservedSET_domain_containing_protein[Cytochrome c]-lysine N-methyltransferaseYHL039W-like proteinRkm1pUncharacterized proteinActin-histidine N-methyltransferaseSET domain containing protein, putativeSET domain containing protein, putativePredicted proteinN-lysine methyltransferase SETD6 isoform X3Chromosome 1, whole genome shotgun sequenceRubisco LSMT substrate-binding, putativehistone-lysine N-methyltransferase setd3-like isoform X2SET domain-containing proteinUncharacterized protein[Ribulose-bisphosphate-carboxylase]-lysine N-methyltransferaseSET (Trithorax/polycomb) domain containingUncharacterized proteinSET domain protein (AFU_orthologue AFUA_4G11040)Hypothetical_protein_-_conservedUncharacterized proteinHypothetical_protein_-_conservedExpressed proteinSET domain-containing proteinSET domain-containing protein 6SET domain-containing proteinUncharacterized proteinSET domain-containing proteinUncharacterized proteinSET domain-containing protein 4SET (Trithorax/polycomb) domain containingUncharacterized proteinRubisco small subunit small subunit n-methyltransferaseHistone-lysine N-methyltransferase setd3Cytoplasmic proteinCIA6Uncharacterized proteinPredicted proteinUncharacterized proteinProtein N-methyltransferasePredicted proteinPredicted proteinUncharacterized proteinUncharacterized proteinN-lysine methyltransferaseUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized proteinYALI0F30327pPredicted proteinUncharacterized proteinPredicted proteinYALI0E34397pPredicted proteinUncharacterized proteinMIP03820pSET domain containing protein, putativeProtein-lysine N-methyltransferaseUncharacterized proteinProtein-lysine N-methyltransferaseUncharacterized proteinRibosomal lysine N-methyltransferase 4Uncharacterized proteinSET domain containing protein, putativeYALI0F20944pProtein-lysine N-methyltransferaseUncharacterized proteinUncharacterized proteinUncharacterized proteinRubisco large subunit N-methyltransferasePredicted proteinUncharacterized proteinPredicted proteinLysine N-methylaseUncharacterized proteinHistone-lysine N-methyltransferase setd3-like ProteinUncharacterized proteinUncharacterized proteinRibosomal lysine N-methyltransferase 4CIA6N-lysine methyltransferaseUncharacterized proteinAFL100WpUncharacterized proteinPredicted proteinSET domain-containing protein 8Ribosomal lysine N-methyltransferase set11Predicted proteinHistone-lysine N-methyltransferase setd3-like ProteinUncharacterized proteinUncharacterized protein (Fragment)Uncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinSET domain-containing 4Uncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinPredicted proteinADR237CpPredicted proteinUncharacterized proteinCytochrome c lysine N-methyltransferase 1AGAP013401-PAPredicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized protein C16C6.01cUncharacterized proteinPredicted proteinPredicted proteinRubisco small subunit N-methyltransferaseUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinN-lysine methyltransferase SETD6Predicted proteinPredicted proteinPredicted proteinPredicted proteinUncharacterized proteinUncharacterized proteinChromosome 9, whole genome shotgun sequenceUncharacterized proteinChromosome 9, whole genome shotgun sequenceUncharacterized proteinChromosome 9, whole genome shotgun sequenceN-lysine methyltransferaseUncharacterized proteinUncharacterized protein
« Back to all FunFams

FunFam 7: Ribosomal lysine N-methyltransferase 4

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Protein-lysine N-methyltransferase activity GO:0016279
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate.
6 Q12504 (/IGI) Q12504 (/IGI) Q12504 (/IGI) Q12504 (/IGI) Q12504 (/IGI) Q12504 (/IGI)
Protein-lysine N-methyltransferase activity GO:0016279
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate.
6 Q12504 (/IMP) Q12504 (/IMP) Q12504 (/IMP) Q12504 (/IMP) Q12504 (/IMP) Q12504 (/IMP)
Protein-lysine N-methyltransferase activity GO:0016279
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate.
1 Q9P6L2 (/IDA)
Showing 1 to 3 of 3 entries

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Peptidyl-lysine monomethylation GO:0018026
The methylation of peptidyl-lysine to form peptidyl-N6-methyl-L-lysine.
6 Q12504 (/IGI) Q12504 (/IGI) Q12504 (/IGI) Q12504 (/IGI) Q12504 (/IGI) Q12504 (/IGI)
Peptidyl-lysine monomethylation GO:0018026
The methylation of peptidyl-lysine to form peptidyl-N6-methyl-L-lysine.
6 Q12504 (/IMP) Q12504 (/IMP) Q12504 (/IMP) Q12504 (/IMP) Q12504 (/IMP) Q12504 (/IMP)
Regulation of cytoplasmic translation in response to stress GO:1990497
Modulation of the frequency, rate or extent of cytoplasmic translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
1 Q9P6L2 (/IMP)
Showing 1 to 3 of 3 entries

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
7 Q12504 (/HDA) Q12504 (/HDA) Q12504 (/HDA) Q12504 (/HDA) Q12504 (/HDA) Q12504 (/HDA) Q9P6L2 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9P6L2 (/IDA)
Showing 1 to 2 of 2 entries
CATH-Gene3D is a Global Biodata Core Resource Learn more...