The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Molybdopterin biosynthesis MoaE subunit
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Molybdopterin synthase catalytic subunit

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Molybdopterin synthase activity GO:0030366
Catalysis of the conversion of precursor Z to molybdopterin, the final step in molybdopterin biosynthesis.
17 A4FUY7 (/ISS) B3M268 (/ISS) B3P6R5 (/ISS) B4GE20 (/ISS) B4IJG7 (/ISS) B4JHP4 (/ISS) B4KBH3 (/ISS) B4LVP8 (/ISS) B4NJW0 (/ISS) B4PUD1 (/ISS)
(7 more)
Molybdopterin synthase activity GO:0030366
Catalysis of the conversion of precursor Z to molybdopterin, the final step in molybdopterin biosynthesis.
2 O96007 (/IDA) O96007 (/IDA)
Molybdopterin synthase activity GO:0030366
Catalysis of the conversion of precursor Z to molybdopterin, the final step in molybdopterin biosynthesis.
2 O96007 (/TAS) O96007 (/TAS)
Molybdopterin synthase activity GO:0030366
Catalysis of the conversion of precursor Z to molybdopterin, the final step in molybdopterin biosynthesis.
1 Q9Z223 (/ISO)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q9Z223 (/IPI)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mo-molybdopterin cofactor biosynthetic process GO:0006777
The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.
17 A4FUY7 (/ISS) B3M268 (/ISS) B3P6R5 (/ISS) B4GE20 (/ISS) B4IJG7 (/ISS) B4JHP4 (/ISS) B4KBH3 (/ISS) B4LVP8 (/ISS) B4NJW0 (/ISS) B4PUD1 (/ISS)
(7 more)
Mo-molybdopterin cofactor biosynthetic process GO:0006777
The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.
2 O96007 (/IDA) O96007 (/IDA)
Molybdopterin cofactor biosynthetic process GO:0032324
The chemical reactions and pathways resulting in the formation of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.
2 O96007 (/TAS) O96007 (/TAS)
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
1 Q9VBX2 (/IDA)
Mo-molybdopterin cofactor biosynthetic process GO:0006777
The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.
1 Q9Z223 (/ISO)
Histone acetylation GO:0016573
The modification of a histone by the addition of an acetyl group.
1 Q9VBX2 (/IDA)
Molybdopterin cofactor biosynthetic process GO:0032324
The chemical reactions and pathways resulting in the formation of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.
1 Q9VBX2 (/IMP)

There are 14 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
17 A4FUY7 (/ISS) B3M268 (/ISS) B3P6R5 (/ISS) B4GE20 (/ISS) B4IJG7 (/ISS) B4JHP4 (/ISS) B4KBH3 (/ISS) B4LVP8 (/ISS) B4NJW0 (/ISS) B4PUD1 (/ISS)
(7 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 A0A024QZS1 (/IDA) A0A024QZS1 (/IDA) O96007 (/IDA) O96007 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 A0A024QZS1 (/IDA) A0A024QZS1 (/IDA) O96007 (/IDA) O96007 (/IDA)
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
4 A0A024QZS1 (/IDA) A0A024QZS1 (/IDA) O96007 (/IDA) O96007 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 O96007 (/TAS) O96007 (/TAS)
Molybdopterin synthase complex GO:0019008
A protein complex that possesses molybdopterin synthase activity. In E. coli, the complex is a heterotetramer consisting of two MoaD and two MoaE subunits.
2 O96007 (/IPI) O96007 (/IPI)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9Z223 (/ISO)
Ada2/Gcn5/Ada3 transcription activator complex GO:0005671
A multiprotein complex that possesses histone acetyltransferase and is involved in regulation of transcription. Contains either GCN5 or PCAF in a mutually exclusive manner. The budding yeast complex includes Gcn5p, two proteins of the Ada family, and two TBP-associate proteins (TAFs); analogous complexes in other species have analogous compositions, and usually contain homologs of the yeast proteins. Both ATAC- or SAGA (see GO:0000124, SAGA complex) are involved in the acetylation of histone H3K9 and K14 residues.
1 Q9VBX2 (/IDA)
Ada2/Gcn5/Ada3 transcription activator complex GO:0005671
A multiprotein complex that possesses histone acetyltransferase and is involved in regulation of transcription. Contains either GCN5 or PCAF in a mutually exclusive manner. The budding yeast complex includes Gcn5p, two proteins of the Ada family, and two TBP-associate proteins (TAFs); analogous complexes in other species have analogous compositions, and usually contain homologs of the yeast proteins. Both ATAC- or SAGA (see GO:0000124, SAGA complex) are involved in the acetylation of histone H3K9 and K14 residues.
1 Q9VBX2 (/IPI)
Polytene chromosome GO:0005700
A type of chromosome in a polyploid cell, formed when multiple copies of homologous chromosomes are aligned side by side to give a giant chromosome in which distinct chromosome bands are readily visible.
1 Q9VBX2 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9Z223 (/ISO)
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
1 Q9Z223 (/ISO)
Molybdopterin synthase complex GO:0019008
A protein complex that possesses molybdopterin synthase activity. In E. coli, the complex is a heterotetramer consisting of two MoaD and two MoaE subunits.
1 Q9VBX2 (/IDA)
Molybdopterin synthase complex GO:0019008
A protein complex that possesses molybdopterin synthase activity. In E. coli, the complex is a heterotetramer consisting of two MoaD and two MoaE subunits.
1 Q9Z223 (/ISO)
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