The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"F-actin capping protein, beta subunit
".
FunFam 4: F-actin-capping protein subunit beta
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
6 | P13517 (/IPI) P13517 (/IPI) P13517 (/IPI) P13517 (/IPI) P13517 (/IPI) P13517 (/IPI) |
Actin filament binding GO:0051015
Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.
|
6 | P13517 (/IMP) P13517 (/IMP) P13517 (/IMP) P13517 (/IMP) P13517 (/IMP) P13517 (/IMP) |
Actin filament binding GO:0051015
Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.
|
1 | Q9HGP5 (/IDA) |
There are 13 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Barbed-end actin filament capping GO:0051016
The binding of a protein or protein complex to the barbed (or plus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.
|
7 | P13517 (/IDA) P13517 (/IDA) P13517 (/IDA) P13517 (/IDA) P13517 (/IDA) P13517 (/IDA) Q9HGP5 (/IDA) |
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
|
6 | P13517 (/IMP) P13517 (/IMP) P13517 (/IMP) P13517 (/IMP) P13517 (/IMP) P13517 (/IMP) |
Actin filament organization GO:0007015
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.
|
2 | Q9M9G7 (/IMP) Q9M9G7 (/IMP) |
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
|
2 | Q9M9G7 (/IMP) Q9M9G7 (/IMP) |
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
|
2 | Q9M9G7 (/IMP) Q9M9G7 (/IMP) |
Actin filament capping GO:0051693
The binding of a protein or protein complex to the end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.
|
2 | Q9M9G7 (/IMP) Q9M9G7 (/IMP) |
Actin cortical patch organization GO:0044396
A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane in cells, at sites of endocytosis.
|
1 | Q9HGP5 (/IGI) |
Actin cortical patch organization GO:0044396
A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane in cells, at sites of endocytosis.
|
1 | Q9HGP5 (/IMP) |
Negative regulation of actin filament annealing GO:0110055
Any process that stops, prevents or reduces the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments.
|
1 | Q9HGP5 (/IDA) |
Mitotic actomyosin contractile ring contraction GO:1902404
Any actomyosin contractile ring contraction that is involved in mitotic cell cycle.
|
1 | Q9HGP5 (/IMP) |
Mitotic actomyosin contractile ring assembly GO:1903475
Any actomyosin contractile ring assembly that is involved in mitotic cytokinesis.
|
1 | Q9HGP5 (/IGI) |
Positive regulation of Arp2/3 complex-mediated actin nucleation GO:2000601
Any process that activates or increases the frequency, rate or extent of Arp2/3 complex-mediated actin nucleation.
|
1 | Q9HGP5 (/IDA) |
Negative regulation of barbed-end actin filament capping GO:2000813
Any process that stops, prevents or reduces the frequency, rate or extent of barbed-end actin filament capping.
|
1 | Q9HGP5 (/IDA) |
There are 16 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
F-actin capping protein complex GO:0008290
A heterodimer consisting of alpha and beta subunits that binds to and caps the barbed ends of actin filaments, thereby regulating the polymerization of actin monomers but not severing actin filaments.
|
7 | P13517 (/IDA) P13517 (/IDA) P13517 (/IDA) P13517 (/IDA) P13517 (/IDA) P13517 (/IDA) Q9HGP5 (/IDA) |
Actin cortical patch GO:0030479
An endocytic patch that consists of an actin-containing structure found at the plasma membrane in cells; formed of networks of branched actin filaments that lie just beneath the plasma membrane and assemble, move, and disassemble rapidly. An example of this is the actin cortical patch found in Saccharomyces cerevisiae.
|
7 | P13517 (/IDA) P13517 (/IDA) P13517 (/IDA) P13517 (/IDA) P13517 (/IDA) P13517 (/IDA) Q9HGP5 (/IDA) |
Incipient cellular bud site GO:0000131
The portion of the budding yeast plasma membrane where a daughter cell will emerge. The yeast marks this spot with bud-site selection proteins before bud emergence occurs. Actin is polarized to this spot just prior to and during bud emergence.
|
6 | P13517 (/IDA) P13517 (/IDA) P13517 (/IDA) P13517 (/IDA) P13517 (/IDA) P13517 (/IDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
6 | P13517 (/HDA) P13517 (/HDA) P13517 (/HDA) P13517 (/HDA) P13517 (/HDA) P13517 (/HDA) |
Cellular bud tip GO:0005934
The end of a cellular bud distal to the site of attachment to the mother cell.
|
6 | P13517 (/HDA) P13517 (/HDA) P13517 (/HDA) P13517 (/HDA) P13517 (/HDA) P13517 (/HDA) |
Cellular bud tip GO:0005934
The end of a cellular bud distal to the site of attachment to the mother cell.
|
6 | P13517 (/IDA) P13517 (/IDA) P13517 (/IDA) P13517 (/IDA) P13517 (/IDA) P13517 (/IDA) |
F-actin capping protein complex GO:0008290
A heterodimer consisting of alpha and beta subunits that binds to and caps the barbed ends of actin filaments, thereby regulating the polymerization of actin monomers but not severing actin filaments.
|
6 | P13517 (/IMP) P13517 (/IMP) P13517 (/IMP) P13517 (/IMP) P13517 (/IMP) P13517 (/IMP) |
Mating projection tip GO:0043332
The apex of the mating projection in unicellular fungi exposed to mating pheromone; site of polarized growth.
|
6 | P13517 (/HDA) P13517 (/HDA) P13517 (/HDA) P13517 (/HDA) P13517 (/HDA) P13517 (/HDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q9HGP5 (/HDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q9HGP5 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9HGP5 (/HDA) |
Medial cortex GO:0031097
A medial cortical band overlaying the nucleus which acts as a landmark for contractile ring positioning and plays a role in cell cycle regulation.
|
1 | Q9HGP5 (/IDA) |
Cell division site GO:0032153
The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
|
1 | Q9HGP5 (/HDA) |
Cell division site GO:0032153
The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
|
1 | Q9HGP5 (/IDA) |
Mating projection tip GO:0043332
The apex of the mating projection in unicellular fungi exposed to mating pheromone; site of polarized growth.
|
1 | Q9HGP5 (/IDA) |
Actin body GO:0099079
An amorphous cytoskeletal structure consisting of aggregated actin filaments and associated proteins (including fibrin and capping protein) in which there is little or no actin filament turnover. In yeast (S. pombe and S. cerevisiae) these are found only in quiescent cells and are thought to serve as a reserve store of actin.
|
1 | Q9HGP5 (/IDA) |