The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Aspartate Aminotransferase, domain 1
".
FunFam 33: Cystathionine gamma-synthase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cystathionine gamma-synthase activity GO:0003962
Catalysis of the reaction: O-succinyl-L-homoserine + L-cysteine = cystathionine + succinate.
|
2 | P55217 (/IDA) P55217 (/IDA) |
|
Cystathionine gamma-synthase activity GO:0003962
Catalysis of the reaction: O-succinyl-L-homoserine + L-cysteine = cystathionine + succinate.
|
2 | P55217 (/ISS) P55217 (/ISS) |
|
Pyridoxal phosphate binding GO:0030170
Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
|
2 | P55217 (/IDA) P55217 (/IDA) |
|
O-acetylhomoserine aminocarboxypropyltransferase activity GO:0003961
Catalysis of the reaction: O-acetyl-L-homoserine + methanethiol = L-methionine + acetate. Also reacts with other thiols and H2S, producing homocysteine or thioethers.
|
1 | Q5LTI3 (/ISS) |
|
Cystathionine gamma-lyase activity GO:0004123
Catalysis of the reaction: L-cystathionine + H2O = 2-oxobutanoate + L-cysteine + NH4+.
|
1 | E9AFE7 (/TAS) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Methionine biosynthetic process GO:0009086
The chemical reactions and pathways resulting in the formation of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.
|
7 | P55217 (/IMP) P55217 (/IMP) P55218 (/IMP) P55218 (/IMP) P55218 (/IMP) P55218 (/IMP) P55218 (/IMP) |
|
Selenium compound metabolic process GO:0001887
The chemical reactions and pathways involving compounds that contain selenium, such as selenocysteine.
|
2 | P55217 (/IDA) P55217 (/IDA) |
|
Cysteine metabolic process GO:0006534
The chemical reactions and pathways involving cysteine, 2-amino-3-mercaptopropanoic acid.
|
1 | Q5LTI3 (/ISS) |
|
Methionine metabolic process GO:0006555
The chemical reactions and pathways involving methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.
|
1 | Q5LTI3 (/ISS) |
|
Sulfur compound metabolic process GO:0006790
The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.
|
1 | Q5LTI3 (/ISS) |
|
Posttranscriptional regulation of gene expression GO:0010608
Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript.
|
1 | Q38DH3 (/IDA) |
|
L-methionine biosynthetic process from L-homoserine via cystathionine GO:0019279
The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including L-homoserine, via the intermediate cystathionine.
|
1 | O94350 (/IC) |
|
S-adenosylhomocysteine catabolic process GO:0019510
The chemical reactions and pathways resulting in the breakdown of S-adenosylhomocysteine, forming homocysteine and then methionine.
|
1 | E9AFE7 (/TAS) |
There are 7 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
|
2 | P55217 (/IDA) P55217 (/IDA) |
|
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
|
2 | P55217 (/IDA) P55217 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q38DH3 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | E9AFE7 (/ISO) |
|
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
|
1 | O94350 (/ISS) |
|
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
|
1 | Q38DH3 (/IDA) |
|
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
|
1 | E9AFE7 (/ISO) |
