CATH Superfamily 3.90.110.10
Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
".
FunFam 4: Malate dehydrogenase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Malic enzyme activity GO:0004470
Catalysis of the oxidative decarboxylation of malate with the concomitant production of pyruvate.
|
121 |
Q6HSF4 (/ISS)
Q6HSF4 (/ISS)
Q6HSF4 (/ISS)
Q6HSF4 (/ISS)
Q6HSF4 (/ISS)
Q6HSF4 (/ISS)
Q6HSF4 (/ISS)
Q6HSF4 (/ISS)
Q6HSF4 (/ISS)
Q6HSF4 (/ISS)
(111 more) |
|
L-lactate dehydrogenase activity GO:0004459
Catalysis of the reaction: (S)-lactate + NAD+ = pyruvate + NADH + H+.
|
10 | Q8IE66 (/ISS) Q8IE66 (/ISS) Q8IE66 (/ISS) Q8IE66 (/ISS) Q8IE66 (/ISS) Q8IE66 (/ISS) Q8IE66 (/ISS) Q8IE66 (/ISS) Q8IE66 (/ISS) Q8IE66 (/ISS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
5 | P49814 (/IPI) P49814 (/IPI) P49814 (/IPI) P49814 (/IPI) P49814 (/IPI) |
|
L-malate dehydrogenase activity GO:0030060
Catalysis of the reaction: (S)-malate + NAD+ = oxaloacetate + NADH + H+.
|
4 | Q2GK85 (/ISS) Q2GK85 (/ISS) Q2GK85 (/ISS) Q5LXE1 (/ISS) |
|
Malate dehydrogenase activity GO:0016615
Catalysis of the reversible conversion of pyruvate or oxaloacetate to malate.
|
1 | Q74D53 (/ISS) |
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Tricarboxylic acid cycle GO:0006099
A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.
|
126 |
Q2GK85 (/ISS)
Q2GK85 (/ISS)
Q2GK85 (/ISS)
Q5LXE1 (/ISS)
Q6HSF4 (/ISS)
Q6HSF4 (/ISS)
Q6HSF4 (/ISS)
Q6HSF4 (/ISS)
Q6HSF4 (/ISS)
Q6HSF4 (/ISS)
(116 more) |
|
Lactate metabolic process GO:0006089
The chemical reactions and pathways involving lactate, the anion of lactic acid.
|
10 | Q8IE66 (/ISS) Q8IE66 (/ISS) Q8IE66 (/ISS) Q8IE66 (/ISS) Q8IE66 (/ISS) Q8IE66 (/ISS) Q8IE66 (/ISS) Q8IE66 (/ISS) Q8IE66 (/ISS) Q8IE66 (/ISS) |
|
Pyruvate metabolic process GO:0006090
The chemical reactions and pathways involving pyruvate, 2-oxopropanoate.
|
10 | Q8IE66 (/ISS) Q8IE66 (/ISS) Q8IE66 (/ISS) Q8IE66 (/ISS) Q8IE66 (/ISS) Q8IE66 (/ISS) Q8IE66 (/ISS) Q8IE66 (/ISS) Q8IE66 (/ISS) Q8IE66 (/ISS) |
There are 0 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
