The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Ribonuclease Inhibitor
".
FunFam 218: Probable E3 ubiquitin-protein ligase ipaH7.8
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
46 |
A0A0H3NF38 (/IPI)
A0A0H3NF38 (/IPI)
A0A0H3NF38 (/IPI)
A0A0H3NF38 (/IPI)
A0A0H3NF38 (/IPI)
A0A0H3NF38 (/IPI)
A0A0H3NF38 (/IPI)
A0A0H3NF38 (/IPI)
A0A0H3NF38 (/IPI)
A0A0H3NF38 (/IPI)
(36 more) |
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
29 |
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
(19 more) |
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
26 |
B2TT54 (/ISS)
B2TT54 (/ISS)
D0ZRB2 (/ISS)
D0ZRB2 (/ISS)
D0ZRB2 (/ISS)
D2AJU0 (/ISS)
D2AJU0 (/ISS)
D2AJU0 (/ISS)
D2AJU0 (/ISS)
P0CE12 (/ISS)
(16 more) |
|
Catalytic activity GO:0003824
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
|
14 |
P0CE12 (/IMP)
P0CE12 (/IMP)
P0CE12 (/IMP)
P0CE12 (/IMP)
P0CE12 (/IMP)
P0CE12 (/IMP)
P0CE12 (/IMP)
P0CE12 (/IMP)
P0CE12 (/IMP)
P0CE12 (/IMP)
(4 more) |
|
Ubiquitin protein ligase activity GO:0061630
Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.
|
14 |
P0CE12 (/IMP)
P0CE12 (/IMP)
P0CE12 (/IMP)
P0CE12 (/IMP)
P0CE12 (/IMP)
P0CE12 (/IMP)
P0CE12 (/IMP)
P0CE12 (/IMP)
P0CE12 (/IMP)
P0CE12 (/IMP)
(4 more) |
|
Unfolded protein binding GO:0051082
Interacting selectively and non-covalently with an unfolded protein.
|
10 | Q8ZQQ2 (/IPI) Q8ZQQ2 (/IPI) Q8ZQQ2 (/IPI) Q8ZQQ2 (/IPI) Q8ZQQ2 (/IPI) Q8ZQQ2 (/IPI) Q8ZQQ2 (/IPI) Q8ZQQ2 (/IPI) Q8ZQQ2 (/IPI) Q8ZQQ2 (/IPI) |
|
Ubiquitin protein ligase activity GO:0061630
Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.
|
3 | D0ZRB2 (/IDA) D0ZRB2 (/IDA) D0ZRB2 (/IDA) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | Q8VSC3 (/IPI) |
There are 16 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
31 |
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
(21 more) |
|
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
|
26 |
B2TT54 (/ISS)
B2TT54 (/ISS)
D0ZRB2 (/ISS)
D0ZRB2 (/ISS)
D0ZRB2 (/ISS)
D2AJU0 (/ISS)
D2AJU0 (/ISS)
D2AJU0 (/ISS)
D2AJU0 (/ISS)
P0CE12 (/ISS)
(16 more) |
|
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
|
25 |
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
(15 more) |
|
Protein secretion by the type III secretion system GO:0030254
The process in which proteins are transferred into the extracellular milieu or directly into host cells by the bacterial type III secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins.
|
24 |
P0CE12 (/ISS)
P0CE12 (/ISS)
P0CE12 (/ISS)
P0CE12 (/ISS)
P0CE12 (/ISS)
P0CE12 (/ISS)
P0CE12 (/ISS)
P0CE12 (/ISS)
P0CE12 (/ISS)
P0CE12 (/ISS)
(14 more) |
|
Protein secretion by the type III secretion system GO:0030254
The process in which proteins are transferred into the extracellular milieu or directly into host cells by the bacterial type III secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins.
|
21 |
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
(11 more) |
|
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
17 |
D0ZRB2 (/ISS)
D0ZRB2 (/ISS)
D0ZRB2 (/ISS)
P0CE12 (/ISS)
P0CE12 (/ISS)
P0CE12 (/ISS)
P0CE12 (/ISS)
P0CE12 (/ISS)
P0CE12 (/ISS)
P0CE12 (/ISS)
(7 more) |
|
Positive regulation of plant-type hypersensitive response GO:0034052
Any process that activates or increases the frequency, rate or extent of the hypersensitive response in a plant.
|
14 |
P0CE12 (/IMP)
P0CE12 (/IMP)
P0CE12 (/IMP)
P0CE12 (/IMP)
P0CE12 (/IMP)
P0CE12 (/IMP)
P0CE12 (/IMP)
P0CE12 (/IMP)
P0CE12 (/IMP)
P0CE12 (/IMP)
(4 more) |
|
Positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway GO:0070430
Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.
|
14 |
P0CE12 (/IMP)
P0CE12 (/IMP)
P0CE12 (/IMP)
P0CE12 (/IMP)
P0CE12 (/IMP)
P0CE12 (/IMP)
P0CE12 (/IMP)
P0CE12 (/IMP)
P0CE12 (/IMP)
P0CE12 (/IMP)
(4 more) |
|
Positive regulation of interleukin-8 secretion GO:2000484
Any process that activates or increases the frequency, rate or extent of interleukin-8 secretion.
|
14 |
P0CE12 (/IDA)
P0CE12 (/IDA)
P0CE12 (/IDA)
P0CE12 (/IDA)
P0CE12 (/IDA)
P0CE12 (/IDA)
P0CE12 (/IDA)
P0CE12 (/IDA)
P0CE12 (/IDA)
P0CE12 (/IDA)
(4 more) |
|
Negative regulation of protein binding GO:0032091
Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.
|
10 | Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) |
|
Protein K27-linked ubiquitination GO:0044314
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 27 of the ubiquitin monomers, is added to a protein.
|
9 | B2TT54 (/ISS) B2TT54 (/ISS) D2AJU0 (/ISS) D2AJU0 (/ISS) D2AJU0 (/ISS) D2AJU0 (/ISS) Q31SH3 (/ISS) Q326Z6 (/ISS) Q3YTH5 (/ISS) |
|
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
|
4 | D0ZVG2 (/TAS) D0ZVG2 (/TAS) D0ZVG2 (/TAS) D0ZVG2 (/TAS) |
|
Positive regulation of cell death GO:0010942
Any process that increases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
|
3 | D0ZRB2 (/IMP) D0ZRB2 (/IMP) D0ZRB2 (/IMP) |
|
Negative regulation of thioredoxin peroxidase activity GO:1903124
Any process that stops, prevents or reduces the frequency, rate or extent of thioredoxin peroxidase activity.
|
3 | D0ZRB2 (/IMP) D0ZRB2 (/IMP) D0ZRB2 (/IMP) |
|
Protein K27-linked ubiquitination GO:0044314
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 27 of the ubiquitin monomers, is added to a protein.
|
1 | Q8VSC3 (/IDA) |
|
Modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade GO:0085032
Any process in which an organism modulates the frequency, rate or extent of host NF-kappaB-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
|
1 | Q8VSC3 (/IDA) |
There are 9 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Host cell plasma membrane GO:0020002
The plasma membrane surrounding a host cell.
|
14 |
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
D0ZPH9 (/IDA)
(4 more) |
|
Host cell cytoplasm GO:0030430
The cytoplasm of a host cell.
|
10 | Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) |
|
Host cell endoplasmic reticulum GO:0044165
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the host cell cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The host ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
10 | Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) Q8ZQQ2 (/IDA) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
9 | P18009 (/IDA) P18009 (/IDA) P18009 (/IDA) P18014 (/IDA) P18014 (/IDA) P18014 (/IDA) P18014 (/IDA) P18014 (/IDA) Q8VSC3 (/IDA) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
9 | B2TT54 (/ISS) B2TT54 (/ISS) D2AJU0 (/ISS) D2AJU0 (/ISS) D2AJU0 (/ISS) D2AJU0 (/ISS) Q31SH3 (/ISS) Q326Z6 (/ISS) Q3YTH5 (/ISS) |
|
Host cell nucleus GO:0042025
A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.
|
9 | B2TT54 (/ISS) B2TT54 (/ISS) D2AJU0 (/ISS) D2AJU0 (/ISS) D2AJU0 (/ISS) D2AJU0 (/ISS) Q31SH3 (/ISS) Q326Z6 (/ISS) Q3YTH5 (/ISS) |
|
Host cell cytosol GO:0044164
The part of the host cell cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
9 | B2TT54 (/ISS) B2TT54 (/ISS) D2AJU0 (/ISS) D2AJU0 (/ISS) D2AJU0 (/ISS) D2AJU0 (/ISS) Q31SH3 (/ISS) Q326Z6 (/ISS) Q3YTH5 (/ISS) |
|
Host cell nucleus GO:0042025
A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.
|
5 | D0ZVG2 (/IDA) D0ZVG2 (/IDA) D0ZVG2 (/IDA) D0ZVG2 (/IDA) Q8VSC3 (/IDA) |
|
Host cell cytosol GO:0044164
The part of the host cell cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q8VSC3 (/IDA) |
