The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"PPM-type phosphatase domain
".
FunFam 3: PH domain and leucine-rich repeat protein phosphat...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein serine/threonine phosphatase activity GO:0004722
Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
|
2 | D4A254 (/IDA) Q9WTR8 (/IDA) |
|
Protein serine/threonine phosphatase activity GO:0004722
Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
|
2 | Q8BXA7 (/ISO) Q8CHE4 (/ISO) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | O60346 (/IPI) Q6ZVD8 (/IPI) |
There are 25 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
|
2 | D4A254 (/IDA) Q9WTR8 (/IDA) |
|
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
|
2 | Q8BXA7 (/ISO) Q8CHE4 (/ISO) |
|
Hippocampus development GO:0021766
The progression of the hippocampus over time from its initial formation until its mature state.
|
2 | D4A254 (/IEP) Q9WTR8 (/IEP) |
|
Negative regulation of protein kinase B signaling GO:0051898
Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
|
2 | O60346 (/IMP) Q9WTR8 (/IMP) |
|
Negative regulation of protein kinase B signaling GO:0051898
Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
|
2 | O60346 (/TAS) Q6ZVD8 (/TAS) |
|
Regulation of protein phosphorylation GO:0001932
Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.
|
1 | Q9WTR8 (/IMP) |
|
Regulation of protein phosphorylation GO:0001932
Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.
|
1 | Q8CHE4 (/ISO) |
|
Regulation of T cell anergy GO:0002667
Any process that modulates the frequency, rate, or extent of T cell anergy.
|
1 | Q8CHE4 (/IMP) |
|
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
|
1 | Q9WTR8 (/IMP) |
|
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
|
1 | Q9WTR8 (/IEP) |
|
Entrainment of circadian clock GO:0009649
The synchronization of a circadian rhythm to environmental time cues such as light.
|
1 | Q8CHE4 (/IMP) |
|
Regulation of apoptotic process GO:0042981
Any process that modulates the occurrence or rate of cell death by apoptotic process.
|
1 | O60346 (/IDA) |
|
Regulation of apoptotic process GO:0042981
Any process that modulates the occurrence or rate of cell death by apoptotic process.
|
1 | Q8CHE4 (/ISO) |
|
Regulation of MAPK cascade GO:0043408
Any process that modulates the frequency, rate or extent of signal transduction mediated by the MAP kinase (MAPK) cascade.
|
1 | O60346 (/IMP) |
|
Regulation of MAPK cascade GO:0043408
Any process that modulates the frequency, rate or extent of signal transduction mediated by the MAP kinase (MAPK) cascade.
|
1 | Q8CHE4 (/ISO) |
|
Regulation of JNK cascade GO:0046328
Any process that modulates the frequency, rate or extent of signal transduction mediated by the JNK cascade.
|
1 | O60346 (/IDA) |
|
Regulation of JNK cascade GO:0046328
Any process that modulates the frequency, rate or extent of signal transduction mediated by the JNK cascade.
|
1 | Q8CHE4 (/ISO) |
|
Positive regulation of protein kinase B signaling GO:0051897
Any process that activates or increases the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
|
1 | Q8CHE4 (/ISO) |
|
Negative regulation of protein kinase B signaling GO:0051898
Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
|
1 | Q8CHE4 (/ISO) |
|
Negative regulation of ERK1 and ERK2 cascade GO:0070373
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
|
1 | Q8CHE4 (/ISO) |
|
Positive regulation of protein kinase C signaling GO:0090037
Any process that increases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
|
1 | Q8CHE4 (/ISO) |
|
Negative regulation of protein kinase C signaling GO:0090038
Any process that decreases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
|
1 | Q9WTR8 (/IMP) |
|
Negative regulation of protein kinase C signaling GO:0090038
Any process that decreases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
|
1 | Q8CHE4 (/ISO) |
|
Regulation of p38MAPK cascade GO:1900744
Any process that modulates the frequency, rate or extent of p38MAPK cascade.
|
1 | O60346 (/IDA) |
|
Regulation of p38MAPK cascade GO:1900744
Any process that modulates the frequency, rate or extent of p38MAPK cascade.
|
1 | Q8CHE4 (/ISO) |
There are 12 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
3 | D4A254 (/IDA) Q6ZVD8 (/IDA) Q9WTR8 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q8BXA7 (/ISO) Q8CHE4 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | O60346 (/TAS) Q6ZVD8 (/TAS) |
|
Photoreceptor inner segment GO:0001917
The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.
|
1 | D4A254 (/IDA) |
|
Photoreceptor inner segment GO:0001917
The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.
|
1 | Q8BXA7 (/ISO) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q9WTR8 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q8CHE4 (/ISO) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q8CHE4 (/ISO) |
|
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
|
1 | Q9WTR8 (/IDA) |
|
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
|
1 | Q8CHE4 (/ISO) |
|
Photoreceptor outer segment membrane GO:0042622
The membrane surrounding the outer segment of a vertebrate photoreceptor.
|
1 | D4A254 (/IDA) |
|
Photoreceptor outer segment membrane GO:0042622
The membrane surrounding the outer segment of a vertebrate photoreceptor.
|
1 | Q8BXA7 (/ISO) |
