The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.
Functional Families
Superfamily: Metallo-dependent phosphatases
Purple acid phosphatases PMID:10438611, DNA double-strand break repair nucleases PMID:11371344, 5'-nucleotidases (syn. UDP-sugar hydrolase), protein serine/threonine phosphatase, phosphoesterase-related proteins, TT1561-like proteins, YfcE-like proteins, hypothetical protein aq_1666, DR1281-like proteins, TTHA0625-like proteins, GpdQ-like proteins and ADPRibase-Mn-like proteins.
Metallophosphatases (MPPs), also known as metallophosphoesterases, phosphodiesterases (PDEs), binuclear metallophosphoesterases, and dimetal-containing phosphoesterases (DMPs), represent a diverse superfamily of enzymes with a conserved domain containing an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues PMID:18757371,PMID:25837850.
GO Diversity
EC Diversity
Species Diversity
Sequence/Structure Diversity
Superfamily Summary
| Structures | |
|---|---|
| Domains: | 457 |
| Domain clusters (>95% seq id): | 67 |
| Domain clusters (>35% seq id): | 43 |
| Unique PDBs: | 229 |
| Alignments | |
| Structural Clusters (5A): | 12 |
| Structural Clusters (9A): | 5 |
| FunFam Clusters: | 497 |
| Function | |
| Unique EC: | 24 |
| Unique GO: | 770 |
| Taxonomy | |
| Unique Species: | 23087 |
