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CATH Superfamily 3.60.20.10

Aminohydrolase, N-terminal nucleophile (Ntn) domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 11: Amidophosphoribosyltransferase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Amidophosphoribosyltransferase activity GO:0004044
Catalysis of the reaction: 5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + L-glutamine + H(2)O.
 96 P04046 (/IDA) P04046 (/IDA) P04046 (/IDA) P04046 (/IDA) P04046 (/IDA) P04046 (/IDA) P04046 (/IDA) P04046 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA)
(86 more)
Transferase activity, transferring glycosyl groups GO:0016757
Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor).
 87 P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA)
(77 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
 87 P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA)
(77 more)
Amidophosphoribosyltransferase activity GO:0004044
Catalysis of the reaction: 5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + L-glutamine + H(2)O.
 8 P04046 (/IMP) P04046 (/IMP) P04046 (/IMP) P04046 (/IMP) P04046 (/IMP) P04046 (/IMP) P04046 (/IMP) P04046 (/IMP)
Amidophosphoribosyltransferase activity GO:0004044
Catalysis of the reaction: 5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + L-glutamine + H(2)O.
 6 Q9KT99 (/ISS) Q9KT99 (/ISS) Q9KT99 (/ISS) Q9KT99 (/ISS) Q9KT99 (/ISS) Q9KT99 (/ISS)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Purine nucleotide biosynthetic process GO:0006164
The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
 87 P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA)
(77 more)
Glutamine metabolic process GO:0006541
The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid.
 87 P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA)
(77 more)
Glutamine metabolic process GO:0006541
The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid.
 87 P0AG16 (/IMP) P0AG16 (/IMP) P0AG16 (/IMP) P0AG16 (/IMP) P0AG16 (/IMP) P0AG16 (/IMP) P0AG16 (/IMP) P0AG16 (/IMP) P0AG16 (/IMP) P0AG16 (/IMP)
(77 more)
'de novo' IMP biosynthetic process GO:0006189
The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate, by the stepwise assembly of a purine ring on ribose 5-phosphate.
 8 P04046 (/IMP) P04046 (/IMP) P04046 (/IMP) P04046 (/IMP) P04046 (/IMP) P04046 (/IMP) P04046 (/IMP) P04046 (/IMP)
Purine ribonucleotide biosynthetic process GO:0009152
The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
 6 Q9KT99 (/ISS) Q9KT99 (/ISS) Q9KT99 (/ISS) Q9KT99 (/ISS) Q9KT99 (/ISS) Q9KT99 (/ISS)
'de novo' IMP biosynthetic process GO:0006189
The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate, by the stepwise assembly of a purine ring on ribose 5-phosphate.
 1 P41390 (/ISO)
Purine nucleobase biosynthetic process GO:0009113
The chemical reactions and pathways resulting in the formation of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.
 1 P41390 (/IC)
Adenine metabolic process GO:0046083
The chemical reactions and pathways involving adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.
 1 P41390 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
 87 P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA)
(77 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 87 P0AG16 (/HDA) P0AG16 (/HDA) P0AG16 (/HDA) P0AG16 (/HDA) P0AG16 (/HDA) P0AG16 (/HDA) P0AG16 (/HDA) P0AG16 (/HDA) P0AG16 (/HDA) P0AG16 (/HDA)
(77 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 87 P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA) P0AG16 (/IDA)
(77 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
 9 P04046 (/HDA) P04046 (/HDA) P04046 (/HDA) P04046 (/HDA) P04046 (/HDA) P04046 (/HDA) P04046 (/HDA) P04046 (/HDA) P41390 (/HDA)
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