The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Ribonuclease Z/Hydroxyacylglutathione hydrolase-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1Cleavage and polyadenylation specificity factorRibonuclease JDNA cross-link repair 1BCleavage and polyadenylation specificity factor subunit 2SC:2Metallo-beta-lactamase family proteinSC:3Probable L-ascorbate-6-phosphate lactonase UlaGZinc phosphodiesterase ELAC protein 1Phosphonate metabolism protein PhnPSC:4Metallo-beta-lactamase NDM-1Lactamase beta 2Class B metallo-beta-lactamaseMetallo-beta-lactamase type 2Quinolone signal response proteinMetallo-beta-lactamase L1 type 3Metallo-beta-lactamase type 2SC:5N-acyl homoserine lactonase family proteinN-acyl homoserine lactonase AiiAAcylhomoserine lactonaseRibonuclease ZIntegrator complex subunit 11Cleavage and polyadenylation specificity factor subunit 3MBL fold metallo-hydrolaseCleavage and polyadenylation specificity factor subunit 2Anaerobic nitric oxide reductase flavorubredoxinDNA cross-link repair 1Aintegrator complex subunit 9Hydroxyacylglutathione hydrolasePersulfide dioxygenase ETHE1, mitochondrialZinc phosphodiesterase ELAC protein 2probable hydrolase PNKD isoform X1N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D, putativeDNA cross-link repair 1CHydroxyacylglutathione hydrolase, mitochondrialZinc phosphodiesterase ELAC protein 2Inactive cytidine monophosphate-N-acetylneuraminic acid hydroxylasemetallo-beta-lactamase domain-containing protein 2DNA ligase 6Integrator complex subunit 11 isoform X3Cyclic nucleotide-binding domain proteinintegrator complex subunit 11 isoform X2Metallo-hydrolase/oxidoreductase superfamily proteinMBL fold metallo-hydrolaseDNA internalization-related competence protein ComEC/Rec2tRNAse Z4DNA cross-link repair protein pso2/snm1DNA repair metallo-beta-lactamase family proteinBeta-lactamaseMetallo-beta-lactamase domain proteinCleavage and polyadenylation specificity factor,putativeCleavage and polyadenylation specificity factor subunit 3Hydroxyacylglutathione hydrolaseHydroxyacylglutathione hydrolaseCleavage and polyadenylation specificity factor subunit 3integrator complex subunit 11 isoform X2Zn-dependent hydrolase/oxidoreductase family protein, putativetRNase Z TRZ1Ribonuclease Z, mitochondrialtRNAse Z TRZ4, mitochondrialprotein artemis isoform X2Metallo-beta-lactamase superfamily proteinCleavage and polyadenylation specificity factor proteinintegrator complex subunit 9Ribonuclease ZDNA repair metallo-beta-lactamase-domain-containing proteinN-acetylphosphatidylethanolamine-hydrolyzing phospholipase DInterstrand crosslink repair proteinDNA repair metallo-beta-lactamase proteintRNA processing endoribonuclease Trz1, putativeProbable 3',5'-cyclic-nucleotide phosphodiesteraseRibonuclease ZHydroxyacylglutathione hydrolaseMetallo-beta-lactamase family proteinRibonuclease Z, mitochondrialElaC ribonuclease Z 1Glyoxylase, beta-lactamase superfamily IIRibonuclease JMBL fold metallo-hydrolaseHydroxyacylglutathione hydrolaseRibonuclease ZCleavage and polyadenylation specificity factor,putativeRibonuclease JRibonuclease Z, putativeMetallo-hydrolase/oxidoreductase, putativeRibonuclease Z, mitochondrialUnplaced genomic scaffold supercont1.4, whole genome shotgun sequenceDNA repair protein, putativeUnplaced genomic scaffold supercont1.4, whole genome shotgun sequenceUnplaced genomic scaffold supercont1.7, whole genome shotgun sequenceRibonuclease ZRibonuclease ZMBL fold metallo-hydrolasePossible hydrolaseDNA repair proteintRNA processing endoribonuclease Trz1, putativeUnplaced genomic scaffold supercont2.4, whole genome shotgun sequenceUnplaced genomic scaffold supercont2.4, whole genome shotgun sequenceProbable metallo-hydrolase MT2357Metallo-hydrolase/oxidoreductase superfamily proteinMetallo-beta-lactamase type 2MBL fold metallo-hydrolaseRibonuclease Z3',5'-cyclic-nucleotide phosphodiesterasePossible bifunctional enzyme: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase + cyclase/dehydrasePutative metallo-beta-lactamase domain proteinCleavage and polyadenylation specificity factor subunit 2ETHE1, persulfide dioxygenaseRibonuclease ZRibonuclease ZMoRTal germlineDNA cross-link repair 1CCleavage and polyadenylation specificity factor subunit 2Bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferasecAMP-specific phosphodiesteraseMBL fold metallo-hydrolaseMetallo-beta-lactamase domain containing proteinHydroxyacylglutathione hydrolaseProtein CBG11581Cleavage and polyadenylation specificity factor 73 kDa subunitCleavage and polyadenylation specificity factor, putativeDNA cross-link repair 1A protein, variantDNA internalization-related competence protein ComEC/Rec2Beta lactamase like proteinCleavage and polyadenylation specificity factor, 73 kDa subunitMetallo-beta-lactamase domain containing proteinMetallo-beta-lactamase domain containing proteinDNA repair metallo-beta-lactamase, putativeN-acyl-phosphatidylethanolamine-hydrolyzing phospholipase DGlyoxylase, beta-lactamase superfamily IIBeta-lactamase superfamily domain/DNA repair metallo-beta-lactamase, putativeUnplaced genomic scaffold supercont2.2, whole genome shotgun sequenceN-acyl-phosphatidylethanolamine-hydrolyzing phospholipase DMetallo-beta-lactamase superfamily proteinZn-dependent hydrolases, including glyoxylasesMBL fold metallo-hydrolaseCleavage and polyadenylation specificity factor, 73 kDa subunitMetallo-beta-lactamase superfamily proteinRibonuclease ZN-Acyl Phosphatidyl Ethanolamine specific phospholipase D (NAPE-PLD) homologPutative metallo-beta-lactamaseHypothetical_protein_-_conservedRibonuclease ZRibonuclease JRibonuclease Z 1Chromosome 10, whole genome shotgun sequenceMBL fold metallo-hydrolasePredicted proteinPredicted proteinMBL fold metallo-hydrolaseBeta-lactamaseCleavage and polyadenylation specific factor 3Glyoxalase IIUnplaced genomic scaffold supercont2.13, whole genome shotgun sequenceSubunit of mRNA cleavage and polyadenylation specificity factorCleavage and polyadenylation specificity factor subunit 2Cleavage and polyadenylation specificity factor subunit 2Metallo-hydrolase/oxidoreductaseRibonuclease Z, putativeRibonuclease Z 2, mitochondrialMBL fold metallo-hydrolaseRhodanese domain protein / beta-lactamase domain proteinRhodanese domain protein / beta-lactamase domain proteinPredicted proteinDNA repair protein, putative (AFU_orthologue AFUA_1G04570)Uncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinMBL fold metallo-hydrolaseUncharacterized proteinMetallo-beta-lactamase family proteinBeta-lactamase superfamily domain/DNA repair metallo-beta-lactamase, putativeIntegrator complex subunit 11 isoform X3ElaC ribonuclease Z 2MBL fold metallo-hydrolaseSlr2005 proteinBeta-lactamase domain proteinMBL fold metallo-hydrolaseHydroxyacylglutathione hydrolase 3, mitochondrialUncharacterized proteinRibonuclease ZMetal-dependent hydrolase, beta-lactamase superfamily IIIUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinProstate cancer susceptibility protein-like proteinBeta-lactamase-like proteinPutative metallo-beta-lactamase-like proteinProstate cancer susceptibility protein-like proteinUncharacterized proteinFlavo-diiron protein FprA1Rubredoxin:oxygen/nitric oxide oxidoreductaseFlavo-diiron protein FprA2Protein artemisUncharacterized proteinPredicted proteinMetallo-beta-lactamase superfamily proteinRibonuclease Z 2, mitochondrialCPSF3L proteinUncharacterized proteinPredicted proteinChromosome 9, whole genome shotgun sequencePredicted proteinDNA cross-link repair 1CUncharacterized proteinUncharacterized proteinArtemis-related DNA-crosslink repair exonucleasePredicted proteinChromosome 1, whole genome shotgun sequenceUncharacterized proteinDNA repair metallo-beta-lactamase family proteinCPSF3L proteinUncharacterized proteinUncharacterized proteinDNA repair protein, putativeChromosome 1, whole genome shotgun sequenceUncharacterized proteinUncharacterized proteinUncharacterized proteinOs09g0439000 proteinChromosome 10, whole genome shotgun sequenceUncharacterized proteinUncharacterized proteinArtemis-related DNA-crosslink repair exonucleaseCleavage and polyadenylation specificity factor 73-like ProteinUncharacterized proteinRibonuclease ZMetallo-beta-lactamase fold-containing protein ST1585Zinc metallohydrolase, glyoxalase II familyArylsulfataseYALI0E32527pUncharacterized proteinUncharacterized proteinProtein CBR-NAPE-2Uncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinPredicted proteinCoenzyme PQQ synthesis protein BElaC ribonuclease Z 1Uncharacterized proteinPutative hydrolase C777.06c7,8-dihydropterin-6-methyl-4-(beta-D-ribofuranosyl)-aminobenzene-5'-phosphate synthasePredicted proteinRibonuclease ZUncharacterized proteinRNA-metabolising metallo-beta-lactamase family proteinUncharacterized proteinPredicted proteinRNA-metabolising metallo-beta-lactamase family proteinUncharacterized proteinCleavage and polyadenylation specific factor 3Uncharacterized proteinChromosome 7, whole genome shotgun sequenceRibonuclease Z, putativeUncharacterized proteinElaC ribonuclease Z 2Uncharacterized proteinChromosome 7, whole genome shotgun sequenceUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinRNase Z-like proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinDNA repair metallo-beta-lactamase family proteinPutative DNA interstrand cross-link repair proteinPredicted proteinUncharacterized proteinAGAP000597-PAUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized protein
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FunFam 41: Metallo-beta-lactamase domain protein

GO Diversity

Unique GO annotations
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EC Diversity

Unique EC annotations
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Species Diversity

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Statistics

Members
CATH Domains: 0
Sequences: 28
Annotations
Unique GO: 2
Unique EC: 1
Unique Species: 18
Representative
Rep ID: Q5B0C9/22-212
Inherited Annotations: 0
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