The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Iron/manganese superoxide dismutase, C-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: Superoxide dismutase [Fe]

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Superoxide dismutase activity GO:0004784
Catalysis of the reaction: 2 superoxide + 2 H+ = O2 + hydrogen peroxide.
35 A0A1Q4M3M2 (/ISS) A0A1Q4M3M2 (/ISS) A0A1Q4M3M2 (/ISS) A0A1Q4M3M2 (/ISS) A0A1Q4M3M2 (/ISS) A0A1Q4M3M2 (/ISS) A0A1Q4M3M2 (/ISS) A0A1Q4M3M2 (/ISS) A0A1Q4M3M2 (/ISS) A0A1Q4M3M2 (/ISS)
(25 more)
Superoxide dismutase activity GO:0004784
Catalysis of the reaction: 2 superoxide + 2 H+ = O2 + hydrogen peroxide.
11 P17550 (/IDA) P9WGE7 (/IDA) P9WGE7 (/IDA) P9WGE7 (/IDA) P9WGE7 (/IDA) P9WGE7 (/IDA) P9WGE7 (/IDA) P9WGE7 (/IDA) P9WGE7 (/IDA) P9WGE7 (/IDA)
(1 more)
Iron ion binding GO:0005506
Interacting selectively and non-covalently with iron (Fe) ions.
10 P9WGE7 (/IDA) P9WGE7 (/IDA) P9WGE7 (/IDA) P9WGE7 (/IDA) P9WGE7 (/IDA) P9WGE7 (/IDA) P9WGE7 (/IDA) P9WGE7 (/IDA) P9WGE7 (/IDA) P9WGE7 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
10 P9WGE7 (/IPI) P9WGE7 (/IPI) P9WGE7 (/IPI) P9WGE7 (/IPI) P9WGE7 (/IPI) P9WGE7 (/IPI) P9WGE7 (/IPI) P9WGE7 (/IPI) P9WGE7 (/IPI) P9WGE7 (/IPI)
IgE binding GO:0019863
Interacting selectively and non-covalently with an immunoglobulin of the IgE isotype.
4 Q92450 (/IDA) Q92450 (/IDA) Q92450 (/IDA) Q92450 (/IDA)
Manganese ion binding GO:0030145
Interacting selectively and non-covalently with manganese (Mn) ions.
4 Q92450 (/IDA) Q92450 (/IDA) Q92450 (/IDA) Q92450 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q9Y8H8 (/IPI)
Metal ion binding GO:0046872
Interacting selectively and non-covalently with any metal ion.
1 Q74E06 (/ISS)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Removal of superoxide radicals GO:0019430
Any process, acting at the cellular level, involved in removing superoxide radicals (O2-) from a cell or organism, e.g. by conversion to dioxygen (O2) and hydrogen peroxide (H2O2).
36 A0A1Q4M3M2 (/ISS) A0A1Q4M3M2 (/ISS) A0A1Q4M3M2 (/ISS) A0A1Q4M3M2 (/ISS) A0A1Q4M3M2 (/ISS) A0A1Q4M3M2 (/ISS) A0A1Q4M3M2 (/ISS) A0A1Q4M3M2 (/ISS) A0A1Q4M3M2 (/ISS) A0A1Q4M3M2 (/ISS)
(26 more)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
10 P9WGE7 (/IMP) P9WGE7 (/IMP) P9WGE7 (/IMP) P9WGE7 (/IMP) P9WGE7 (/IMP) P9WGE7 (/IMP) P9WGE7 (/IMP) P9WGE7 (/IMP) P9WGE7 (/IMP) P9WGE7 (/IMP)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
10 P9WGE7 (/IMP) P9WGE7 (/IMP) P9WGE7 (/IMP) P9WGE7 (/IMP) P9WGE7 (/IMP) P9WGE7 (/IMP) P9WGE7 (/IMP) P9WGE7 (/IMP) P9WGE7 (/IMP) P9WGE7 (/IMP)
Evasion or tolerance by symbiont of host-produced reactive oxygen species GO:0052059
The process in which an organism avoids the effects of reactive oxygen species produced as a defense response by the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
10 P9WGE7 (/TAS) P9WGE7 (/TAS) P9WGE7 (/TAS) P9WGE7 (/TAS) P9WGE7 (/TAS) P9WGE7 (/TAS) P9WGE7 (/TAS) P9WGE7 (/TAS) P9WGE7 (/TAS) P9WGE7 (/TAS)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
10 P9WGE7 (/HDA) P9WGE7 (/HDA) P9WGE7 (/HDA) P9WGE7 (/HDA) P9WGE7 (/HDA) P9WGE7 (/HDA) P9WGE7 (/HDA) P9WGE7 (/HDA) P9WGE7 (/HDA) P9WGE7 (/HDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
10 P9WGE7 (/IDA) P9WGE7 (/IDA) P9WGE7 (/IDA) P9WGE7 (/IDA) P9WGE7 (/IDA) P9WGE7 (/IDA) P9WGE7 (/IDA) P9WGE7 (/IDA) P9WGE7 (/IDA) P9WGE7 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
10 P9WGE7 (/HDA) P9WGE7 (/HDA) P9WGE7 (/HDA) P9WGE7 (/HDA) P9WGE7 (/HDA) P9WGE7 (/HDA) P9WGE7 (/HDA) P9WGE7 (/HDA) P9WGE7 (/HDA) P9WGE7 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
10 P9WGE7 (/TAS) P9WGE7 (/TAS) P9WGE7 (/TAS) P9WGE7 (/TAS) P9WGE7 (/TAS) P9WGE7 (/TAS) P9WGE7 (/TAS) P9WGE7 (/TAS) P9WGE7 (/TAS) P9WGE7 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
10 P9WGE7 (/HDA) P9WGE7 (/HDA) P9WGE7 (/HDA) P9WGE7 (/HDA) P9WGE7 (/HDA) P9WGE7 (/HDA) P9WGE7 (/HDA) P9WGE7 (/HDA) P9WGE7 (/HDA) P9WGE7 (/HDA)
Periplasmic space GO:0042597
The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria).
10 P9WGE7 (/TAS) P9WGE7 (/TAS) P9WGE7 (/TAS) P9WGE7 (/TAS) P9WGE7 (/TAS) P9WGE7 (/TAS) P9WGE7 (/TAS) P9WGE7 (/TAS) P9WGE7 (/TAS) P9WGE7 (/TAS)
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