The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"FAD/NAD(P)-binding domain
".
FunFam 212: Dihydrolipoyl dehydrogenase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Dihydrolipoyl dehydrogenase activity GO:0004148
Catalysis of the reaction: protein N6-(dihydrolipoyl)lysine + NAD+ = protein N6-(lipoyl)lysine + NADH + H+.
|
11 |
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
(1 more) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
11 |
P9WHH9 (/IPI)
P9WHH9 (/IPI)
P9WHH9 (/IPI)
P9WHH9 (/IPI)
P9WHH9 (/IPI)
P9WHH9 (/IPI)
P9WHH9 (/IPI)
P9WHH9 (/IPI)
P9WHH9 (/IPI)
P9WHH9 (/IPI)
(1 more) |
|
Disulfide oxidoreductase activity GO:0015036
Catalysis of the reaction: substrate with reduced sulfide groups = substrate with oxidized disulfide bonds.
|
11 |
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
(1 more) |
|
Oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor GO:0016655
Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.
|
11 |
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
(1 more) |
|
Zymogen binding GO:0035375
Interacting selectively and non-covalently with a zymogen, an enzymatically inactive precursor of an enzyme that is often convertible to an active enzyme by proteolysis.
|
11 |
P9WHH9 (/IPI)
P9WHH9 (/IPI)
P9WHH9 (/IPI)
P9WHH9 (/IPI)
P9WHH9 (/IPI)
P9WHH9 (/IPI)
P9WHH9 (/IPI)
P9WHH9 (/IPI)
P9WHH9 (/IPI)
P9WHH9 (/IPI)
(1 more) |
|
Flavin adenine dinucleotide binding GO:0050660
Interacting selectively and non-covalently with FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.
|
11 |
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
(1 more) |
|
NADH binding GO:0070404
Interacting selectively and non-covalently with the reduced form, NADH, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions.
|
11 |
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
(1 more) |
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cell redox homeostasis GO:0045454
Any process that maintains the redox environment of a cell or compartment within a cell.
|
11 |
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
(1 more) |
|
Cell redox homeostasis GO:0045454
Any process that maintains the redox environment of a cell or compartment within a cell.
|
11 |
P9WHH9 (/TAS)
P9WHH9 (/TAS)
P9WHH9 (/TAS)
P9WHH9 (/TAS)
P9WHH9 (/TAS)
P9WHH9 (/TAS)
P9WHH9 (/TAS)
P9WHH9 (/TAS)
P9WHH9 (/TAS)
P9WHH9 (/TAS)
(1 more) |
|
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
|
11 |
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
(1 more) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
11 |
P9WHH9 (/HDA)
P9WHH9 (/HDA)
P9WHH9 (/HDA)
P9WHH9 (/HDA)
P9WHH9 (/HDA)
P9WHH9 (/HDA)
P9WHH9 (/HDA)
P9WHH9 (/HDA)
P9WHH9 (/HDA)
P9WHH9 (/HDA)
(1 more) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
11 |
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
(1 more) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
11 |
P9WHH9 (/HDA)
P9WHH9 (/HDA)
P9WHH9 (/HDA)
P9WHH9 (/HDA)
P9WHH9 (/HDA)
P9WHH9 (/HDA)
P9WHH9 (/HDA)
P9WHH9 (/HDA)
P9WHH9 (/HDA)
P9WHH9 (/HDA)
(1 more) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
11 |
P9WHH9 (/TAS)
P9WHH9 (/TAS)
P9WHH9 (/TAS)
P9WHH9 (/TAS)
P9WHH9 (/TAS)
P9WHH9 (/TAS)
P9WHH9 (/TAS)
P9WHH9 (/TAS)
P9WHH9 (/TAS)
P9WHH9 (/TAS)
(1 more) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
11 |
P9WHH9 (/HDA)
P9WHH9 (/HDA)
P9WHH9 (/HDA)
P9WHH9 (/HDA)
P9WHH9 (/HDA)
P9WHH9 (/HDA)
P9WHH9 (/HDA)
P9WHH9 (/HDA)
P9WHH9 (/HDA)
P9WHH9 (/HDA)
(1 more) |
|
Pyruvate dehydrogenase complex GO:0045254
Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3).
|
11 |
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
P9WHH9 (/IDA)
(1 more) |
