View in Gene3D

CATH Superfamily 3.50.50.100

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 1: NADH dehydrogenase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
NADH dehydrogenase (ubiquinone) activity GO:0008137
Catalysis of the reaction: NADH + ubiquinone + 5 H(+)(in) <=> NAD(+) + ubiquinol + 4 H(+)(out).
 82 P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA)
(72 more)
Flavin adenine dinucleotide binding GO:0050660
Interacting selectively and non-covalently with FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.
 82 P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA)
(72 more)
NADH dehydrogenase activity GO:0003954
Catalysis of the reaction: NADH + H+ + acceptor = NAD+ + reduced acceptor.
 17 Q606U6 (/ISS) Q888U9 (/ISS) Q888U9 (/ISS) Q888U9 (/ISS) Q888U9 (/ISS) Q888U9 (/ISS) Q888U9 (/ISS) Q888U9 (/ISS) Q888U9 (/ISS) Q888U9 (/ISS)
(7 more)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Aerobic respiration GO:0009060
The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor.
 82 P00393 (/IMP) P00393 (/IMP) P00393 (/IMP) P00393 (/IMP) P00393 (/IMP) P00393 (/IMP) P00393 (/IMP) P00393 (/IMP) P00393 (/IMP) P00393 (/IMP)
(72 more)
Anaerobic respiration GO:0009061
The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which uses compounds other than oxygen (e.g. nitrate, sulfate) as the terminal electron acceptor.
 82 P00393 (/IMP) P00393 (/IMP) P00393 (/IMP) P00393 (/IMP) P00393 (/IMP) P00393 (/IMP) P00393 (/IMP) P00393 (/IMP) P00393 (/IMP) P00393 (/IMP)
(72 more)
Aerobic electron transport chain GO:0019646
A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to oxygen to generate a transmembrane electrochemical gradient.
 82 P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA)
(72 more)
Copper ion homeostasis GO:0055070
Any process involved in the maintenance of an internal steady state of copper ions within an organism or cell.
 82 P00393 (/IMP) P00393 (/IMP) P00393 (/IMP) P00393 (/IMP) P00393 (/IMP) P00393 (/IMP) P00393 (/IMP) P00393 (/IMP) P00393 (/IMP) P00393 (/IMP)
(72 more)
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
 12 Q606U6 (/ISS) Q888U9 (/ISS) Q888U9 (/ISS) Q888U9 (/ISS) Q888U9 (/ISS) Q888U9 (/ISS) Q888U9 (/ISS) Q888U9 (/ISS) Q888U9 (/ISS) Q888U9 (/ISS)
(2 more)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 82 P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA)
(72 more)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
 82 P00393 (/RCA) P00393 (/RCA) P00393 (/RCA) P00393 (/RCA) P00393 (/RCA) P00393 (/RCA) P00393 (/RCA) P00393 (/RCA) P00393 (/RCA) P00393 (/RCA)
(72 more)
NADH dehydrogenase complex GO:0030964
An integral membrane complex that possesses NADH oxidoreductase activity. The complex is one of the components of the electron transport chain. It catalyzes the transfer of a pair of electrons from NADH to a quinone.
 82 P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA) P00393 (/IDA)
(72 more)
CATH-Gene3D is a Global Biodata Core Resource Learn more...