The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Kinesin motor domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 54: Kinesin-like protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Motor activity GO:0003774
Catalysis of the generation of force resulting either in movement along a microfilament or microtubule, or in torque resulting in membrane scission, coupled to the hydrolysis of a nucleoside triphosphate.
3 M9PF35 (/IDA) P91945 (/IDA) Q9VSW5 (/IDA)
Motor activity GO:0003774
Catalysis of the generation of force resulting either in movement along a microfilament or microtubule, or in torque resulting in membrane scission, coupled to the hydrolysis of a nucleoside triphosphate.
3 M9PF35 (/ISS) P91945 (/ISS) Q9VSW5 (/ISS)

There are 14 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Microtubule depolymerization GO:0007019
The removal of tubulin heterodimers from one or both ends of a microtubule.
3 M9PF35 (/IMP) P91945 (/IMP) Q9VSW5 (/IMP)
Mitotic spindle organization GO:0007052
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.
3 M9PF35 (/IMP) P91945 (/IMP) Q9VSW5 (/IMP)
Spindle assembly involved in male meiosis I GO:0007054
The formation of the spindle during meiosis I of a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster.
3 M9PF35 (/IMP) P91945 (/IMP) Q9VSW5 (/IMP)
Chromosome segregation GO:0007059
The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
3 M9PF35 (/IMP) P91945 (/IMP) Q9VSW5 (/IMP)
Male meiosis chromosome segregation GO:0007060
The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a male.
3 M9PF35 (/IMP) P91945 (/IMP) Q9VSW5 (/IMP)
Mitotic centrosome separation GO:0007100
Separation of duplicated centrosome components at the beginning of mitosis. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle.
3 M9PF35 (/IMP) P91945 (/IMP) Q9VSW5 (/IMP)
Meiosis I cytokinesis GO:0007110
A cell cycle process that results in the division of the cytoplasm of a cell after meiosis I, resulting in the separation of the original cell into two daughter cells.
3 M9PF35 (/IMP) P91945 (/IMP) Q9VSW5 (/IMP)
Male meiosis I GO:0007141
A cell cycle process comprising the steps by which a cell progresses through male meiosis I, the first meiotic division in the male germline.
3 M9PF35 (/IMP) P91945 (/IMP) Q9VSW5 (/IMP)
Male meiotic chromosome movement towards spindle pole GO:0016346
The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during male meiosis.
3 M9PF35 (/IMP) P91945 (/IMP) Q9VSW5 (/IMP)
Sister chromatid biorientation GO:0031134
The cell cycle process in which sister chromatids establish stable attachments to microtubules emanating from opposite spindle poles.
3 M9PF35 (/IMP) P91945 (/IMP) Q9VSW5 (/IMP)
Spindle assembly GO:0051225
The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.
3 M9PF35 (/IMP) P91945 (/IMP) Q9VSW5 (/IMP)
Spindle elongation GO:0051231
The cell cycle process in which the distance is lengthened between poles of the spindle.
3 M9PF35 (/IMP) P91945 (/IMP) Q9VSW5 (/IMP)
Generative cell mitosis GO:0055047
The process in which the generative cell divides by mitosis to form two haploid cells. These will subsequently differentiate into sperm cells.
3 M9PF35 (/IMP) P91945 (/IMP) Q9VSW5 (/IMP)
Cytoplasmic microtubule organization GO:0031122
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell.
1 Q6S002 (/IGI)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Kinetochore GO:0000776
A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
3 M9PF35 (/IDA) P91945 (/IDA) Q9VSW5 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 M9PF35 (/IDA) P91945 (/IDA) Q9VSW5 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 M9PF35 (/IDA) P91945 (/IDA) Q9VSW5 (/IDA)
Kinetochore microtubule GO:0005828
Any of the spindle microtubules that attach to the kinetochores of chromosomes by their plus ends, and maneuver the chromosomes during mitotic or meiotic chromosome segregation.
3 M9PF35 (/IDA) P91945 (/IDA) Q9VSW5 (/IDA)
Kinesin complex GO:0005871
Any complex that includes a dimer of molecules from the kinesin superfamily, a group of related proteins that contain an extended region of predicted alpha-helical coiled coil in the main chain that likely produces dimerization. The native complexes of several kinesin family members have also been shown to contain additional peptides, often designated light chains as all of the noncatalytic subunits that are currently known are smaller than the chain that contains the motor unit. Kinesin complexes generally possess a force-generating enzymatic activity, or motor, which converts the free energy of the gamma phosphate bond of ATP into mechanical work.
3 M9PF35 (/TAS) P91945 (/TAS) Q9VSW5 (/TAS)
Microtubule associated complex GO:0005875
Any multimeric complex connected to a microtubule.
3 M9PF35 (/IDA) P91945 (/IDA) Q9VSW5 (/IDA)
Spindle microtubule GO:0005876
Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole.
3 M9PF35 (/IDA) P91945 (/IDA) Q9VSW5 (/IDA)
Mitotic spindle GO:0072686
A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules.
3 M9PF35 (/IDA) P91945 (/IDA) Q9VSW5 (/IDA)
Mitotic spindle midzone GO:1990023
The area in the center of the anaphase spindle consisting of microtubules, microtubule bundling factors and kinesin motors where the spindle microtubules from opposite poles overlap in an antiparallel manner.
3 M9PF35 (/IDA) P91945 (/IDA) Q9VSW5 (/IDA)
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