The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Alkaline Phosphatase, subunit A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 63: Alkaline phosphatase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Alkaline phosphatase activity GO:0004035
Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.
5 P11491 (/IDA) P11491 (/IDA) P11491 (/IDA) P11491 (/IDA) Q54Y02 (/IDA)
Fructose-2,6-bisphosphate 6-phosphatase activity GO:0047386
Catalysis of the reaction: beta-D-fructose 2,6-bisphosphate + H(2)O = beta-D-fructofuranose 2-phosphate + phosphate.
4 P11491 (/IDA) P11491 (/IDA) P11491 (/IDA) P11491 (/IDA)
Alkaline phosphatase activity GO:0004035
Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.
1 Q54Y02 (/IMP)
Alkaline phosphatase activity GO:0004035
Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.
1 O60109 (/ISO)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
4 P11491 (/IDA) P11491 (/IDA) P11491 (/IDA) P11491 (/IDA)
Nicotinamide nucleotide metabolic process GO:0046496
The chemical reactions and pathways involving nicotinamide nucleotides, any nucleotide that contains combined nicotinamide.
4 P11491 (/IMP) P11491 (/IMP) P11491 (/IMP) P11491 (/IMP)
Sorocarp development GO:0030587
The process whose specific outcome is the progression of the sorocarp over time, from its formation to the mature structure. The process begins with the aggregation of individual cells and ends with the mature sorocarp. The sorocarp is a structure containing a spore-bearing sorus that sits on top of a stalk. An example of this process is found in Dictyostelium discoideum.
1 Q54Y02 (/IEP)
Nicotinamide nucleotide metabolic process GO:0046496
The chemical reactions and pathways involving nicotinamide nucleotides, any nucleotide that contains combined nicotinamide.
1 O60109 (/ISO)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Fungal-type vacuole membrane GO:0000329
The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
4 P11491 (/HDA) P11491 (/HDA) P11491 (/HDA) P11491 (/HDA)
Fungal-type vacuole membrane GO:0000329
The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
4 P11491 (/IDA) P11491 (/IDA) P11491 (/IDA) P11491 (/IDA)
Fungal-type vacuole GO:0000324
A vacuole that has both lytic and storage functions. The fungal vacuole is a large, membrane-bounded organelle that functions as a reservoir for the storage of small molecules (including polyphosphate, amino acids, several divalent cations (e.g. calcium), other ions, and other small molecules) as well as being the primary compartment for degradation. It is an acidic compartment, containing an ensemble of acid hydrolases. At least in S. cerevisiae, there are indications that the morphology of the vacuole is variable and correlated with the cell cycle, with logarithmically growing cells having a multilobed, reticulated vacuole, while stationary phase cells contain a single large structure.
1 O60109 (/HDA)
Fungal-type vacuole membrane GO:0000329
The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
1 O60109 (/ISO)
Contractile vacuole GO:0000331
A specialized vacuole of eukaryotic cells, especially Protozoa, that fills with water from the cytoplasm and then discharges this externally by the opening of contractile vacuole pores. Its function is probably osmoregulatory.
1 Q54Y02 (/IDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
1 C8V8B5 (/IDA)
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