View in Gene3D

CATH Superfamily 3.40.640.10

Type I PLP-dependent aspartate aminotransferase-like (Major domain)

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Type I PLP-dependent aspartate aminotransferase-like (Major domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 93: L-tryptophan--pyruvate aminotransferase 1

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Tryptophan transaminase. [EC: 2.6.1.27]
L-tryptophan + 2-oxoglutarate = (indol-3-yl)pyruvate + L-glutamate.
  • Also acts on 5-hydroxytryptophan and, to a lesser extent, on the phenyl amino acids.
 12 A0A0D3EK26 A0A0D3EK26 A0A0D3EK26 I1NKM1 I1NKM1 I1NKM1 Q5VQG8 Q5VQG8 Q5VQG8 Q94A02
(2 more...)
L-tryptophan--pyruvate aminotransferase. [EC: 2.6.1.99]
L-tryptophan + pyruvate = indole-3-pyruvate + L-alanine.
  • This plant enzyme, along with EC 1.14.13.168, is responsible for the biosynthesis of the plant hormone indole-3-acetate from L-tryptophan.
 3 Q94A02 Q9LR29 Q9S7N2
CATH-Gene3D is a Global Biodata Core Resource Learn more...