CATH Superfamily 3.40.640.10
Type I PLP-dependent aspartate aminotransferase-like (Major domain)
The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Type I PLP-dependent aspartate aminotransferase-like (Major domain)
".
FunFam 71: Kynurenine/alpha-aminoadipate aminotransferase, mi...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 9 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Kynurenine-oxoglutarate transaminase activity GO:0016212
Catalysis of the reaction: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate.
|
3 | Q64602 (/IDA) Q8N5Z0 (/IDA) Q8N5Z0 (/IDA) |
|
Kynurenine-oxoglutarate transaminase activity GO:0016212
Catalysis of the reaction: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate.
|
3 | Q5E9N4 (/ISS) Q64602 (/ISS) Q9WVM8 (/ISS) |
|
2-aminoadipate transaminase activity GO:0047536
Catalysis of the reaction: 2-oxoglutarate + L-2-aminoadipate = 2-oxoadipate + L-glutamate.
|
3 | Q5E9N4 (/ISS) Q64602 (/ISS) Q9WVM8 (/ISS) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
2 | Q8N5Z0 (/IPI) Q8N5Z0 (/IPI) |
|
2-aminoadipate transaminase activity GO:0047536
Catalysis of the reaction: 2-oxoglutarate + L-2-aminoadipate = 2-oxoadipate + L-glutamate.
|
2 | Q8N5Z0 (/IDA) Q8N5Z0 (/IDA) |
|
Transaminase activity GO:0008483
Catalysis of the transfer of an amino group to an acceptor, usually a 2-oxo acid.
|
1 | Q64602 (/TAS) |
|
Kynurenine-oxoglutarate transaminase activity GO:0016212
Catalysis of the reaction: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate.
|
1 | Q9WVM8 (/ISO) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | Q9WVM8 (/ISO) |
|
2-aminoadipate transaminase activity GO:0047536
Catalysis of the reaction: 2-oxoglutarate + L-2-aminoadipate = 2-oxoadipate + L-glutamate.
|
1 | Q9WVM8 (/ISO) |
There are 11 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
2-oxoglutarate metabolic process GO:0006103
The chemical reactions and pathways involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is a key constituent of the TCA cycle and a key intermediate in amino-acid metabolism.
|
3 | Q5E9N4 (/ISS) Q64602 (/ISS) Q9WVM8 (/ISS) |
|
Glutamate metabolic process GO:0006536
The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid.
|
3 | Q5E9N4 (/ISS) Q64602 (/ISS) Q9WVM8 (/ISS) |
|
Kynurenine metabolic process GO:0070189
The chemical reactions and pathways involving kynurenine, the amino acid 3-(2-aminobenzoyl)-alanine.
|
3 | Q5E9N4 (/ISS) Q64602 (/ISS) Q9WVM8 (/ISS) |
|
2-oxoglutarate metabolic process GO:0006103
The chemical reactions and pathways involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is a key constituent of the TCA cycle and a key intermediate in amino-acid metabolism.
|
2 | Q8N5Z0 (/IDA) Q8N5Z0 (/IDA) |
|
Glutamate metabolic process GO:0006536
The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid.
|
2 | Q8N5Z0 (/IDA) Q8N5Z0 (/IDA) |
|
Lysine catabolic process GO:0006554
The chemical reactions and pathways resulting in the breakdown of lysine, 2,6-diaminohexanoic acid.
|
2 | Q8N5Z0 (/TAS) Q8N5Z0 (/TAS) |
|
Tryptophan catabolic process GO:0006569
The chemical reactions and pathways resulting in the breakdown of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.
|
2 | Q8N5Z0 (/TAS) Q8N5Z0 (/TAS) |
|
Kynurenine metabolic process GO:0070189
The chemical reactions and pathways involving kynurenine, the amino acid 3-(2-aminobenzoyl)-alanine.
|
2 | Q8N5Z0 (/IDA) Q8N5Z0 (/IDA) |
|
2-oxoglutarate metabolic process GO:0006103
The chemical reactions and pathways involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is a key constituent of the TCA cycle and a key intermediate in amino-acid metabolism.
|
1 | Q9WVM8 (/ISO) |
|
Glutamate metabolic process GO:0006536
The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid.
|
1 | Q9WVM8 (/ISO) |
|
Kynurenine metabolic process GO:0070189
The chemical reactions and pathways involving kynurenine, the amino acid 3-(2-aminobenzoyl)-alanine.
|
1 | Q9WVM8 (/ISO) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
|
2 | Q8N5Z0 (/TAS) Q8N5Z0 (/TAS) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | Q9WVM8 (/HDA) |
