The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Type I PLP-dependent aspartate aminotransferase-like (Major domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 62: Cystathionine beta-lyase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cystathionine beta-lyase activity GO:0004121
Catalysis of the reaction: cystathionine + H2O = L-homocysteine + NH3 + pyruvate.
13 P06721 (/IDA) P06721 (/IDA) P06721 (/IDA) P06721 (/IDA) P06721 (/IDA) P06721 (/IDA) P06721 (/IDA) P06721 (/IDA) P06721 (/IDA) P06721 (/IDA)
(3 more)
Pyridoxal phosphate binding GO:0030170
Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
13 P06721 (/IDA) P06721 (/IDA) P06721 (/IDA) P06721 (/IDA) P06721 (/IDA) P06721 (/IDA) P06721 (/IDA) P06721 (/IDA) P06721 (/IDA) P06721 (/IDA)
(3 more)
L-cysteine desulfhydrase activity GO:0080146
Catalysis of the reaction: L-cysteine + H2O = ammonia + pyruvate + hydrogen sulfide + H+.
13 P06721 (/IMP) P06721 (/IMP) P06721 (/IMP) P06721 (/IMP) P06721 (/IMP) P06721 (/IMP) P06721 (/IMP) P06721 (/IMP) P06721 (/IMP) P06721 (/IMP)
(3 more)
Cystathionine beta-lyase activity GO:0004121
Catalysis of the reaction: cystathionine + H2O = L-homocysteine + NH3 + pyruvate.
8 Q9KRH1 (/ISS) Q9KRH1 (/ISS) Q9KRH1 (/ISS) Q9KRH1 (/ISS) Q9KRH1 (/ISS) Q9KRH1 (/ISS) Q9KRH1 (/ISS) Q9KRH1 (/ISS)

There are 1 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Methionine biosynthetic process GO:0009086
The chemical reactions and pathways resulting in the formation of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.
8 Q9KRH1 (/ISS) Q9KRH1 (/ISS) Q9KRH1 (/ISS) Q9KRH1 (/ISS) Q9KRH1 (/ISS) Q9KRH1 (/ISS) Q9KRH1 (/ISS) Q9KRH1 (/ISS)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
CATH-Gene3D is a Global Biodata Core Resource Learn more...