The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Type I PLP-dependent aspartate aminotransferase-like (Major domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 56: SelA-like pyridoxal phosphate-dependent enzyme

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
D-glucosaminate-6-phosphate ammonia lyase. [EC: 4.3.1.29]
2-amino-2-deoxy-D-gluconate 6-phosphate = 2-dehydro-3-deoxy-6-phospho-D- gluconate + NH(3).
  • The enzyme, from the bacterium Salmonella typhimurium, is involved in the degradation pathway of 2-amino-2-deoxy-D-gluconate.
156 A0A0D6I3R5 A0A0D6I3R5 A0A0D6I3R5 A0A0D6I3R5 A0A0D6I3R5 A0A0D6I3R5 A0A0D6I3R5 A0A0D6I3R5 A0A0D6I3R5 A0A0D6I3R5
(146 more...)
L-seryl-tRNA(Sec) selenium transferase. [EC: 2.9.1.1]
L-seryl-tRNA(Sec) + selenophosphate = L-selenocysteinyl-tRNA(Sec) + phosphate.
  • Recognizes specifically tRNA(Sec)-species.
  • Binding of tRNA(Sec) also occurs in the absence of the seryl group.
  • 2-aminoacryloyl-tRNA, bound to the enzyme as an imine with the pyridoxal phosphate, is an intermediate in the reaction.
  • Since the selenium atom replaces oxygen in serine, the product may also be referred to as L-selenoseryl-tRNA(Sel).
  • The abbreviation Sel has also been used for selenocysteine but Sec is preferred.
1 O67140
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