The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Type I PLP-dependent aspartate aminotransferase-like (Major domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 30: Low-specificity L-threonine aldolase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
L-allo-threonine aldolase activity GO:0008732
Catalysis of the reaction: L-allo-threonine = glycine + acetaldehyde.
11 P37303 (/IDA) P75823 (/IDA) P75823 (/IDA) P75823 (/IDA) P75823 (/IDA) P75823 (/IDA) P75823 (/IDA) P75823 (/IDA) P75823 (/IDA) P75823 (/IDA)
(1 more)
Pyridoxal phosphate binding GO:0030170
Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
10 P75823 (/IDA) P75823 (/IDA) P75823 (/IDA) P75823 (/IDA) P75823 (/IDA) P75823 (/IDA) P75823 (/IDA) P75823 (/IDA) P75823 (/IDA) P75823 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
10 P75823 (/IPI) P75823 (/IPI) P75823 (/IPI) P75823 (/IPI) P75823 (/IPI) P75823 (/IPI) P75823 (/IPI) P75823 (/IPI) P75823 (/IPI) P75823 (/IPI)
Phenylserine aldolase activity GO:0050179
Catalysis of the reaction: L-threo-3-phenylserine = benzaldehyde + glycine.
10 P75823 (/IDA) P75823 (/IDA) P75823 (/IDA) P75823 (/IDA) P75823 (/IDA) P75823 (/IDA) P75823 (/IDA) P75823 (/IDA) P75823 (/IDA) P75823 (/IDA)
Threonine aldolase activity GO:0004793
Catalysis of the reaction: L-threonine = glycine + acetaldehyde.
7 O13940 (/ISS) Q885J1 (/ISS) Q8EC07 (/ISS) Q9KLH9 (/ISS) Q9KLH9 (/ISS) Q9KLH9 (/ISS) Q9KLH9 (/ISS)
Threonine aldolase activity GO:0004793
Catalysis of the reaction: L-threonine = glycine + acetaldehyde.
3 A0A1D8PSW2 (/IMP) Q59NC4 (/IMP) Q59NC4 (/IMP)
L-allo-threonine aldolase activity GO:0008732
Catalysis of the reaction: L-allo-threonine = glycine + acetaldehyde.
2 Q747V3 (/ISS) Q747V3 (/ISS)
Threonine aldolase activity GO:0004793
Catalysis of the reaction: L-threonine = glycine + acetaldehyde.
1 P37303 (/IDA)
Threonine aldolase activity GO:0004793
Catalysis of the reaction: L-threonine = glycine + acetaldehyde.
1 C8VBQ1 (/RCA)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular amino acid metabolic process GO:0006520
The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
5 Q8EC07 (/ISS) Q9KLH9 (/ISS) Q9KLH9 (/ISS) Q9KLH9 (/ISS) Q9KLH9 (/ISS)
Threonine catabolic process GO:0006567
The chemical reactions and pathways resulting in the breakdown of threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins.
3 O13940 (/ISS) Q747V3 (/ISS) Q747V3 (/ISS)
Cellular amino acid metabolic process GO:0006520
The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
1 C8VBQ1 (/RCA)
Glycine biosynthetic process GO:0006545
The chemical reactions and pathways resulting in the formation of glycine, aminoethanoic acid.
1 P37303 (/IDA)
Glycine biosynthetic process GO:0006545
The chemical reactions and pathways resulting in the formation of glycine, aminoethanoic acid.
1 O13940 (/ISS)
Threonine catabolic process GO:0006567
The chemical reactions and pathways resulting in the breakdown of threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins.
1 P37303 (/IDA)
Carnitine biosynthetic process GO:0045329
The chemical reactions and pathways resulting in the formation of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
1 A0A1D8PSW2 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
11 P37303 (/IDA) P75823 (/IDA) P75823 (/IDA) P75823 (/IDA) P75823 (/IDA) P75823 (/IDA) P75823 (/IDA) P75823 (/IDA) P75823 (/IDA) P75823 (/IDA)
(1 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 O13940 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O13940 (/HDA)
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