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CATH Superfamily 3.40.640.10

Type I PLP-dependent aspartate aminotransferase-like (Major domain)

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Type I PLP-dependent aspartate aminotransferase-like (Major domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 27: Serine--pyruvate aminotransferase, mitochondrial

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Alanine--glyoxylate transaminase. [EC: 2.6.1.44]
L-alanine + glyoxylate = pyruvate + glycine.
  • With one component of the animal enzyme, 2-oxobutanoate can replace glyoxylate.
  • A second component also catalyzes the reaction of EC 2.6.1.51.
 57 A7A209 A7A209 A7A209 A7A209 A7A209 A7A209 A7A209 B3LUI1 B3LUI1 B3LUI1
(47 more...)
(S)-ureidoglycine--glyoxylate transaminase. [EC: 2.6.1.112]
(S)-ureidoglycine + glyoxylate = N-carbamoyl-2-oxoglycine + glycine.
  • The protein, found in bacteria, can use other amino-group acceptors, but is specific for (S)-ureidoglycine.
 16 A0A164TP40 A0A164TP40 A0A164TP40 A0A164TP40 A0A410R4V0 A0A410R4V0 A0A410R4V0 A0A410R4V0 O32148 O32148
(6 more...)
Serine--pyruvate transaminase. [EC: 2.6.1.51]
L-serine + pyruvate = 3-hydroxypyruvate + L-alanine.
  • The liver enzyme may be identical with EC 2.6.1.44.
 9 O35423 P09139 P21549 P31029 P31030 P41689 Q54GT6 Q5RDP0 Q9X1C0
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