The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Type I PLP-dependent aspartate aminotransferase-like (Major domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 19: Pyridoxal phosphate-dependent aminotransferase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
L-alanine:2-oxoglutarate aminotransferase activity GO:0004021
Catalysis of the reaction: 2-oxoglutarate + L-alanine = L-glutamate + pyruvate.
152 P0A959 (/IDA) P0A959 (/IDA) P0A959 (/IDA) P0A959 (/IDA) P0A959 (/IDA) P0A959 (/IDA) P0A959 (/IDA) P0A959 (/IDA) P0A959 (/IDA) P0A959 (/IDA)
(142 more)
Transaminase activity GO:0008483
Catalysis of the transfer of an amino group to an acceptor, usually a 2-oxo acid.
152 P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP)
(142 more)
Pyridoxal phosphate binding GO:0030170
Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
152 P0A959 (/IDA) P0A959 (/IDA) P0A959 (/IDA) P0A959 (/IDA) P0A959 (/IDA) P0A959 (/IDA) P0A959 (/IDA) P0A959 (/IDA) P0A959 (/IDA) P0A959 (/IDA)
(142 more)
L-aspartate:2-oxoglutarate aminotransferase activity GO:0004069
Catalysis of the reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.
9 Q9KQM1 (/ISS) Q9KQM1 (/ISS) Q9KQM1 (/ISS) Q9KQM1 (/ISS) Q9KQM1 (/ISS) Q9KQM1 (/ISS) Q9KQM1 (/ISS) Q9KQM1 (/ISS) Q9KQM1 (/ISS)
L-alanine:2-oxoglutarate aminotransferase activity GO:0004021
Catalysis of the reaction: 2-oxoglutarate + L-alanine = L-glutamate + pyruvate.
1 P71348 (/ISS)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
D-alanine biosynthetic process GO:0030632
The chemical reactions and pathways resulting in the formation of D-alanine, the D-enantiomer of the amino acid alanine, i.e (2R)-2-aminopropanoic acid.
305 P0A960 (/ISS) P0A960 (/ISS) P0A960 (/ISS) P0A960 (/ISS) P0A960 (/ISS) P0A960 (/ISS) P0A960 (/ISS) P0A960 (/ISS) P0A960 (/ISS) P0A960 (/ISS)
(295 more)
Alanine biosynthetic process GO:0006523
The chemical reactions and pathways resulting in the formation of alanine, 2-aminopropanoic acid.
152 P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP)
(142 more)
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
152 P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP)
(142 more)
L-alanine biosynthetic process from pyruvate GO:0019272
The chemical reactions and pathways resulting in the formation of alanine from other compounds, including pyruvate.
152 P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP)
(142 more)
D-alanine biosynthetic process GO:0030632
The chemical reactions and pathways resulting in the formation of D-alanine, the D-enantiomer of the amino acid alanine, i.e (2R)-2-aminopropanoic acid.
152 P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP)
(142 more)
Response to antibiotic GO:0046677
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
152 P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP) P0A959 (/IMP)
(142 more)
Aspartate biosynthetic process GO:0006532
The chemical reactions and pathways resulting in the formation of aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid.
9 Q9KQM1 (/ISS) Q9KQM1 (/ISS) Q9KQM1 (/ISS) Q9KQM1 (/ISS) Q9KQM1 (/ISS) Q9KQM1 (/ISS) Q9KQM1 (/ISS) Q9KQM1 (/ISS) Q9KQM1 (/ISS)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
11 P9WQ91 (/HDA) P9WQ91 (/HDA) P9WQ91 (/HDA) P9WQ91 (/HDA) P9WQ91 (/HDA) P9WQ91 (/HDA) P9WQ91 (/HDA) P9WQ91 (/HDA) P9WQ91 (/HDA) P9WQ91 (/HDA)
(1 more)
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