CATH Superfamily 3.40.640.10
Type I PLP-dependent aspartate aminotransferase-like (Major domain)
The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Type I PLP-dependent aspartate aminotransferase-like (Major domain)
".
FunFam 153: Serine palmitoyltransferase component
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Serine C-palmitoyltransferase activity GO:0004758
Catalysis of the reaction: L-serine + H(+) + palmitoyl-CoA = 3-dehydrosphinganine + CO(2) + CoA.
|
6 | P25045 (/IGI) P25045 (/IGI) P25045 (/IGI) P25045 (/IGI) P25045 (/IGI) P25045 (/IGI) |
|
Serine C-palmitoyltransferase activity GO:0004758
Catalysis of the reaction: L-serine + H(+) + palmitoyl-CoA = 3-dehydrosphinganine + CO(2) + CoA.
|
6 | P25045 (/IMP) P25045 (/IMP) P25045 (/IMP) P25045 (/IMP) P25045 (/IMP) P25045 (/IMP) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
6 | P25045 (/IPI) P25045 (/IPI) P25045 (/IPI) P25045 (/IPI) P25045 (/IPI) P25045 (/IPI) |
There are 1 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Sphingolipid biosynthetic process GO:0030148
The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
|
6 | P25045 (/IMP) P25045 (/IMP) P25045 (/IMP) P25045 (/IMP) P25045 (/IMP) P25045 (/IMP) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
6 | P25045 (/HDA) P25045 (/HDA) P25045 (/HDA) P25045 (/HDA) P25045 (/HDA) P25045 (/HDA) |
|
Serine C-palmitoyltransferase complex GO:0017059
An enzyme complex that catalyzes the transfer of a palmitoyl on to serine, forming 3-dehydro-D-sphinganine.
|
6 | P25045 (/IMP) P25045 (/IMP) P25045 (/IMP) P25045 (/IMP) P25045 (/IMP) P25045 (/IMP) |
|
SPOTS complex GO:0035339
A multiprotein complex at least composed of serine palmitoyltransferases and ORM proteins (known as ORMDL proteins in mammals and other higher vertebrates) that plays a key role in sphingolipid homeostasis.
|
6 | P25045 (/IDA) P25045 (/IDA) P25045 (/IDA) P25045 (/IDA) P25045 (/IDA) P25045 (/IDA) |
