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CATH Superfamily 3.40.640.10

Type I PLP-dependent aspartate aminotransferase-like (Major domain)

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Type I PLP-dependent aspartate aminotransferase-like (Major domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 13: 4-aminobutyrate aminotransferase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
4-aminobutyrate transaminase activity GO:0003867
Catalysis of the reaction: 4-aminobutanoate + amino group acceptor = succinate semialdehyde + amino acid.
 36 P22256 (/IDA) P22256 (/IDA) P22256 (/IDA) P22256 (/IDA) P22256 (/IDA) P22256 (/IDA) P22256 (/IDA) P22256 (/IDA) P22256 (/IDA) P22256 (/IDA)
(26 more)
Pyridoxal phosphate binding GO:0030170
Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
 36 P22256 (/IDA) P22256 (/IDA) P22256 (/IDA) P22256 (/IDA) P22256 (/IDA) P22256 (/IDA) P22256 (/IDA) P22256 (/IDA) P22256 (/IDA) P22256 (/IDA)
(26 more)
5-aminovalerate transaminase activity GO:0047589
Catalysis of the reaction: 2-oxoglutarate + 5-aminopentanoate = 5-oxopentanoate + L-glutamate.
 27 Q88RB9 (/IDA) Q88RB9 (/IDA) Q88RB9 (/IDA) Q88RB9 (/IDA) Q88RB9 (/IDA) Q88RB9 (/IDA) Q88RB9 (/IDA) Q88RB9 (/IDA) Q88RB9 (/IDA) Q88RB9 (/IDA)
(17 more)
N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity GO:0003992
Catalysis of the reaction: 2-oxoglutarate + N(2)-acetyl-L-ornithine = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate.
 13 P22256 (/IDA) P22256 (/IDA) P22256 (/IDA) P22256 (/IDA) P22256 (/IDA) P22256 (/IDA) P22256 (/IDA) P22256 (/IDA) P22256 (/IDA) P22256 (/IDA)
(3 more)
4-aminobutyrate transaminase activity GO:0003867
Catalysis of the reaction: 4-aminobutanoate + amino group acceptor = succinate semialdehyde + amino acid.
 4 P94427 (/IMP) P94427 (/IMP) P94427 (/IMP) P94427 (/IMP)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Putrescine catabolic process GO:0009447
The chemical reactions and pathways resulting in the breakdown of putrescine, 1,4-diaminobutane; putrescine is the metabolic precursor of spermidine and spermine.
 23 P50457 (/IMP) P50457 (/IMP) P50457 (/IMP) P50457 (/IMP) P50457 (/IMP) P50457 (/IMP) P50457 (/IMP) P50457 (/IMP) P50457 (/IMP) P50457 (/IMP)
(13 more)
L-lysine catabolic process GO:0019477
The chemical reactions and pathways resulting in the breakdown of L-lysine, the L-enantiomer of (S)-2,6-diaminohexanoic acid.
 19 Q88RB9 (/IMP) Q88RB9 (/IMP) Q88RB9 (/IMP) Q88RB9 (/IMP) Q88RB9 (/IMP) Q88RB9 (/IMP) Q88RB9 (/IMP) Q88RB9 (/IMP) Q88RB9 (/IMP) Q88RB9 (/IMP)
(9 more)
Gamma-aminobutyric acid catabolic process GO:0009450
The chemical reactions and pathways resulting in the breakdown of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.
 13 P22256 (/IMP) P22256 (/IMP) P22256 (/IMP) P22256 (/IMP) P22256 (/IMP) P22256 (/IMP) P22256 (/IMP) P22256 (/IMP) P22256 (/IMP) P22256 (/IMP)
(3 more)
Arginine biosynthetic process via ornithine GO:0042450
The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound ornithine.
 13 P22256 (/IGI) P22256 (/IGI) P22256 (/IGI) P22256 (/IGI) P22256 (/IGI) P22256 (/IGI) P22256 (/IGI) P22256 (/IGI) P22256 (/IGI) P22256 (/IGI)
(3 more)
L-lysine catabolic process GO:0019477
The chemical reactions and pathways resulting in the breakdown of L-lysine, the L-enantiomer of (S)-2,6-diaminohexanoic acid.
 8 Q9I6M4 (/IDA) Q9I6M4 (/IDA) Q9I6M4 (/IDA) Q9I6M4 (/IDA) Q9I6M4 (/IDA) Q9I6M4 (/IDA) Q9I6M4 (/IDA) Q9I6M4 (/IDA)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 13 P22256 (/IDA) P22256 (/IDA) P22256 (/IDA) P22256 (/IDA) P22256 (/IDA) P22256 (/IDA) P22256 (/IDA) P22256 (/IDA) P22256 (/IDA) P22256 (/IDA)
(3 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 11 P9WQ79 (/HDA) P9WQ79 (/HDA) P9WQ79 (/HDA) P9WQ79 (/HDA) P9WQ79 (/HDA) P9WQ79 (/HDA) P9WQ79 (/HDA) P9WQ79 (/HDA) P9WQ79 (/HDA) P9WQ79 (/HDA)
(1 more)
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