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CATH Superfamily 3.40.640.10

Type I PLP-dependent aspartate aminotransferase-like (Major domain)

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Type I PLP-dependent aspartate aminotransferase-like (Major domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 12: alanine aminotransferase 2

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Alanine transaminase. [EC: 2.6.1.2]
L-alanine + 2-oxoglutarate = pyruvate + L-glutamate.
  • 2-aminobutanoate acts slowly instead of alanine.
 83 A0A024R6R2 A0A024R6R2 A0A024R6R2 A0A024R6R2 A0A178WFM8 A0A178WFM8 A0A178WG36 A0A178WG36 A0A287ESQ2 A0A287ESQ2
(73 more...)
Glycine transaminase. [EC: 2.6.1.4]
Glycine + 2-oxoglutarate = glyoxylate + L-glutamate.
    		 8 A0A178WFM8 A0A178WFM8 A0A178WG36 A0A178WG36 Q9LR30 Q9LR30 Q9S7E9 Q9S7E9
    Alanine--glyoxylate transaminase. [EC: 2.6.1.44]
    L-alanine + glyoxylate = pyruvate + glycine.
    • With one component of the animal enzyme, 2-oxobutanoate can replace glyoxylate.
    • A second component also catalyzes the reaction of EC 2.6.1.51.
    		 8 A0A178WFM8 A0A178WFM8 A0A178WG36 A0A178WG36 Q9LR30 Q9LR30 Q9S7E9 Q9S7E9
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