The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Type I PLP-dependent aspartate aminotransferase-like (Major domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 108: Serine hydroxymethyltransferase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glycine hydroxymethyltransferase activity GO:0004372
Catalysis of the reaction: 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine.
12 Q8I566 (/TAS) Q8I566 (/TAS) Q8I566 (/TAS) Q8I566 (/TAS) Q8I566 (/TAS) Q8I566 (/TAS) Q8I566 (/TAS) Q8I566 (/TAS) Q8I566 (/TAS) Q8I566 (/TAS)
(2 more)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
One-carbon metabolic process GO:0006730
The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states.
12 Q8I566 (/TAS) Q8I566 (/TAS) Q8I566 (/TAS) Q8I566 (/TAS) Q8I566 (/TAS) Q8I566 (/TAS) Q8I566 (/TAS) Q8I566 (/TAS) Q8I566 (/TAS) Q8I566 (/TAS)
(2 more)
D-serine metabolic process GO:0070178
The chemical reactions and pathways involving D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid.
12 Q8I566 (/IDA) Q8I566 (/IDA) Q8I566 (/IDA) Q8I566 (/IDA) Q8I566 (/IDA) Q8I566 (/IDA) Q8I566 (/IDA) Q8I566 (/IDA) Q8I566 (/IDA) Q8I566 (/IDA)
(2 more)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
12 Q8I566 (/IDA) Q8I566 (/IDA) Q8I566 (/IDA) Q8I566 (/IDA) Q8I566 (/IDA) Q8I566 (/IDA) Q8I566 (/IDA) Q8I566 (/IDA) Q8I566 (/IDA) Q8I566 (/IDA)
(2 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
12 Q8I566 (/IDA) Q8I566 (/IDA) Q8I566 (/IDA) Q8I566 (/IDA) Q8I566 (/IDA) Q8I566 (/IDA) Q8I566 (/IDA) Q8I566 (/IDA) Q8I566 (/IDA) Q8I566 (/IDA)
(2 more)
Apicoplast GO:0020011
The plastid organelle found in apicomplexans.
12 Q8I566 (/IDA) Q8I566 (/IDA) Q8I566 (/IDA) Q8I566 (/IDA) Q8I566 (/IDA) Q8I566 (/IDA) Q8I566 (/IDA) Q8I566 (/IDA) Q8I566 (/IDA) Q8I566 (/IDA)
(2 more)
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