CATH Superfamily 3.40.600.10
DNA mismatch repair MutH/Restriction endonuclease, type II
The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"DNA mismatch repair MutH/Restriction endonuclease, type II
".
FunFam 1: DNA mismatch repair protein MutH
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
29 |
P06722 (/IDA)
P06722 (/IDA)
P06722 (/IDA)
P06722 (/IDA)
P06722 (/IDA)
P06722 (/IDA)
P06722 (/IDA)
P06722 (/IDA)
P06722 (/IDA)
P06722 (/IDA)
(19 more) |
|
Endonuclease activity GO:0004519
Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.
|
29 |
P06722 (/IDA)
P06722 (/IDA)
P06722 (/IDA)
P06722 (/IDA)
P06722 (/IDA)
P06722 (/IDA)
P06722 (/IDA)
P06722 (/IDA)
P06722 (/IDA)
P06722 (/IDA)
(19 more) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
29 |
P06722 (/IPI)
P06722 (/IPI)
P06722 (/IPI)
P06722 (/IPI)
P06722 (/IPI)
P06722 (/IPI)
P06722 (/IPI)
P06722 (/IPI)
P06722 (/IPI)
P06722 (/IPI)
(19 more) |
|
T/G mismatch-specific endonuclease activity GO:0043765
Catalysis of the repair of T/G mismatches arising from deamination of 5-methylcytosine in DNA by nicking double-stranded DNA within the sequence CT(AT)GN or NT(AT)GG next to the mismatched thymidine residue. The incision is mismatch-dependent and strand-specific, in favor of the G-containing strand. The incision serves as a starting point for subsequent excision repair by DNA polymerase I, which excises thymidine and reinserts cytidine.
|
29 |
P06722 (/IDA)
P06722 (/IDA)
P06722 (/IDA)
P06722 (/IDA)
P06722 (/IDA)
P06722 (/IDA)
P06722 (/IDA)
P06722 (/IDA)
P06722 (/IDA)
P06722 (/IDA)
(19 more) |
|
Endodeoxyribonuclease activity GO:0004520
Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.
|
4 | Q9KU56 (/ISS) Q9KU56 (/ISS) Q9KU56 (/ISS) Q9KU56 (/ISS) |
|
Type II site-specific deoxyribonuclease activity GO:0009036
Catalysis of the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates and 3' hydroxyls. Cleavage is dependent on the presence in the DNA of a specific recognition site; cleavage occurs at or very near this recognition site.
|
1 | Q8EH99 (/ISS) |
There are 4 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of DNA recombination GO:0000018
Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents.
|
29 |
P06722 (/IMP)
P06722 (/IMP)
P06722 (/IMP)
P06722 (/IMP)
P06722 (/IMP)
P06722 (/IMP)
P06722 (/IMP)
P06722 (/IMP)
P06722 (/IMP)
P06722 (/IMP)
(19 more) |
|
Mismatch repair GO:0006298
A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.
|
29 |
P06722 (/IDA)
P06722 (/IDA)
P06722 (/IDA)
P06722 (/IDA)
P06722 (/IDA)
P06722 (/IDA)
P06722 (/IDA)
P06722 (/IDA)
P06722 (/IDA)
P06722 (/IDA)
(19 more) |
|
Mismatch repair GO:0006298
A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.
|
29 |
P06722 (/IMP)
P06722 (/IMP)
P06722 (/IMP)
P06722 (/IMP)
P06722 (/IMP)
P06722 (/IMP)
P06722 (/IMP)
P06722 (/IMP)
P06722 (/IMP)
P06722 (/IMP)
(19 more) |
|
Mismatch repair GO:0006298
A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.
|
1 | Q8EH99 (/ISS) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mismatch repair complex GO:0032300
Any complex formed of proteins that act in mismatch repair.
|
29 |
P06722 (/IGI)
P06722 (/IGI)
P06722 (/IGI)
P06722 (/IGI)
P06722 (/IGI)
P06722 (/IGI)
P06722 (/IGI)
P06722 (/IGI)
P06722 (/IGI)
P06722 (/IGI)
(19 more) |
