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CATH Superfamily 3.40.50.880

Class I glutamine amidotransferase (GATase) domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: Anthranilate synthase component II

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Aminodeoxychorismate synthase. [EC: 2.6.1.85]
Chorismate + L-glutamine = 4-amino-4-deoxychorismate + L-glutamate.
  • Composed of two subunits, PabA and PabB.
  • In the absence of PabA and glutamine, PabB converts ammonia and chorismate into 4-amino-4-deoxychorismate.
  • PabA converts glutamine into glutamate only in the presence of stoichiometric amounts of PabB.
  • Coupled with EC 4.1.3.38, to form 4-aminobenzoate.
  • Formerly EC 6.3.5.8.
 3618 A0A069XMV5 A0A069XMV5 A0A069XMV5 A0A069XMV5 A0A069XMV5 A0A069XMV5 A0A069XMV5 A0A069XMV5 A0A069XMV5 A0A069XMV5
(3608 more...)
Anthranilate synthase. [EC: 4.1.3.27]
Chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate.
  • In some organisms, this enzyme is part of a multifunctional protein together with one or more components of the system for biosynthesis of tryptophan (EC 2.4.2.18, EC 4.1.1.48, EC 4.2.1.20 and EC 5.3.1.24).
  • The native enzyme in the complex with uses either glutamine or (less efficiently) NH(3).
  • The enzyme separated from the complex uses NH(3) only.
 205 A0A080VNV3 A0A080VNV3 A0A080VNV3 A0A080VNV3 A0A080VNV3 A0A080VNV3 A0A0E1NM47 A0A0E1NM47 A0A0E1NM47 A0A0E1NM47
(195 more...)
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