The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Isochorismatase-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 11: Pyrazinamidase/nicotinamidase PncA

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nicotinamidase activity GO:0008936
Catalysis of the reaction: nicotinamide + H2O = nicotinate + NH3.
24 I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA)
(14 more)
Manganese ion binding GO:0030145
Interacting selectively and non-covalently with manganese (Mn) ions.
24 I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA)
(14 more)
Iron ion binding GO:0005506
Interacting selectively and non-covalently with iron (Fe) ions.
12 Q50575 (/IDA) Q50575 (/IDA) Q50575 (/IDA) Q50575 (/IDA) Q50575 (/IDA) Q50575 (/IDA) Q50575 (/IDA) Q50575 (/IDA) Q50575 (/IDA) Q50575 (/IDA)
(2 more)
Ferrous iron binding GO:0008198
Interacting selectively and non-covalently with ferrous iron, Fe(II).
12 I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA)
(2 more)
Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016811
Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amide.
12 Q50575 (/IDA) Q50575 (/IDA) Q50575 (/IDA) Q50575 (/IDA) Q50575 (/IDA) Q50575 (/IDA) Q50575 (/IDA) Q50575 (/IDA) Q50575 (/IDA) Q50575 (/IDA)
(2 more)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nicotinamide metabolic process GO:0006769
The chemical reactions and pathways involving nicotinamide, pyridine-3-carboxamide, the amide of nicotinic acid. It is a member of the B complex of vitamins and occurs widely in living organisms.
24 I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA)
(14 more)
Antibiotic metabolic process GO:0016999
The chemical reactions and pathways involving an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms.
12 Q50575 (/IDA) Q50575 (/IDA) Q50575 (/IDA) Q50575 (/IDA) Q50575 (/IDA) Q50575 (/IDA) Q50575 (/IDA) Q50575 (/IDA) Q50575 (/IDA) Q50575 (/IDA)
(2 more)
Drug metabolic process GO:0017144
The chemical reactions and pathways involving a drug, a substance used in the diagnosis, treatment or prevention of a disease; as used here antibiotic substances (see antibiotic metabolism) are considered to be drugs, even if not used in medical or veterinary practice.
12 I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA) I6XD65 (/IDA)
(2 more)
NAD salvage GO:0034355
Any process that generates nicotinamide adenine dinucleotide (NAD) from derivatives of it, without de novo synthesis; salvage is usually from the degradation products nicotinic acid (Na) and nicotinamide (Nam).
12 Q50575 (/IDA) Q50575 (/IDA) Q50575 (/IDA) Q50575 (/IDA) Q50575 (/IDA) Q50575 (/IDA) Q50575 (/IDA) Q50575 (/IDA) Q50575 (/IDA) Q50575 (/IDA)
(2 more)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
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