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CATH Superfamily 3.40.50.740

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: NADH-ubiquinone oxidoreductase 75 kDa subunit, mit...

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
NADH dehydrogenase. [EC: 1.6.99.3]
NADH + acceptor = NAD(+) + reduced acceptor.
  • After preparations have been subjected to certain treatments cytochrome c may act as acceptor.
  • Under normal conditions, two protons are extruded from the cytoplasm or the intramitochondrial or stromal compartment.
  • Present in a mitochondrial complex as EC 7.1.1.2.
  • Formerly EC 1.6.2.1.
 20 A0A2I2ZR47 A0A2I2ZR47 A0A2I2ZR47 A0A2J8WUJ2 A0A2J8WUJ2 E5KRK5 E5KRK5 E5KRK5 P0CB67 P0CB68
(10 more...)
NADH:ubiquinone reductase (H(+)-translocating). [EC: 7.1.1.2]
NADH + ubiquinone + 5 H(+)(In) = NAD(+) + ubiquinol + 4 H(+)(Out).
  • The complex is present in mitochondria and aerobic bacteria.
  • Breakdown of the complex can release EC 1.6.99.3.
  • In photosynthetic bacteria, reversed electron transport through this enzyme can reduce NAD(+) to NADH.
  • Formerly EC 1.6.5.3.
 20 A0A2I2ZR47 A0A2I2ZR47 A0A2I2ZR47 A0A2J8WUJ2 A0A2J8WUJ2 E5KRK5 E5KRK5 E5KRK5 P0CB67 P0CB68
(10 more...)
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