The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"NAD(P)-binding Rossmann-like Domain
".
FunFam 69: Inositol-3-phosphate synthase 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Inositol-3-phosphate synthase activity GO:0004512
Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. This reaction requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form.
|
9 | O97477 (/IDA) P11986 (/IDA) P11986 (/IDA) P11986 (/IDA) P11986 (/IDA) P11986 (/IDA) P42801 (/IDA) P42801 (/IDA) P42801 (/IDA) |
|
Inositol-3-phosphate synthase activity GO:0004512
Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. This reaction requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form.
|
7 | P42800 (/IGI) P42800 (/IGI) P42801 (/IGI) P42801 (/IGI) P42801 (/IGI) Q38862 (/IGI) Q9LX12 (/IGI) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
7 | P42801 (/IPI) P42801 (/IPI) P42801 (/IPI) Q38862 (/IPI) Q54N49 (/IPI) Q9NPH2 (/IPI) Q9NPH2 (/IPI) |
|
Inositol-3-phosphate synthase activity GO:0004512
Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. This reaction requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form.
|
6 | O97477 (/ISS) P42800 (/ISS) P42800 (/ISS) P42801 (/ISS) P42801 (/ISS) P42801 (/ISS) |
|
Inositol-3-phosphate synthase activity GO:0004512
Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. This reaction requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form.
|
3 | Q54N49 (/IMP) Q9NPH2 (/IMP) Q9NPH2 (/IMP) |
|
Inositol-3-phosphate synthase activity GO:0004512
Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. This reaction requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form.
|
1 | Q9JHU9 (/ISO) |
|
Inositol-3-phosphate synthase activity GO:0004512
Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. This reaction requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form.
|
1 | C8VBX3 (/RCA) |
There are 22 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Inositol biosynthetic process GO:0006021
The chemical reactions and pathways resulting in the formation of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.
|
8 | P11986 (/IDA) P11986 (/IDA) P11986 (/IDA) P11986 (/IDA) P11986 (/IDA) P42801 (/IDA) P42801 (/IDA) P42801 (/IDA) |
|
Inositol biosynthetic process GO:0006021
The chemical reactions and pathways resulting in the formation of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.
|
8 | P11986 (/IMP) P11986 (/IMP) P11986 (/IMP) P11986 (/IMP) P11986 (/IMP) P42800 (/IMP) P42800 (/IMP) Q54N49 (/IMP) |
|
Embryo development ending in seed dormancy GO:0009793
The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana.
|
5 | P42801 (/IGI) P42801 (/IGI) P42801 (/IGI) Q38862 (/IGI) Q9LX12 (/IGI) |
|
Myo-inositol hexakisphosphate biosynthetic process GO:0010264
The chemical reactions and pathways resulting in the formation of phytic acid, myo-inositol hexakisphosphate, a regulator of intracellular signaling, a highly abundant animal anti-nutrient and a phosphate and mineral storage compound in plant seeds.
|
4 | P42801 (/IMP) P42801 (/IMP) P42801 (/IMP) Q38862 (/IMP) |
|
Inositol biosynthetic process GO:0006021
The chemical reactions and pathways resulting in the formation of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.
|
3 | O97477 (/ISS) P42800 (/ISS) P42800 (/ISS) |
|
Phosphatidylserine biosynthetic process GO:0006659
The chemical reactions and pathways resulting in the formation of phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine.
|
3 | P42801 (/IMP) P42801 (/IMP) P42801 (/IMP) |
|
Post-embryonic development GO:0009791
The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development.
|
3 | P42801 (/IMP) P42801 (/IMP) P42801 (/IMP) |
|
Inositol biosynthetic process GO:0006021
The chemical reactions and pathways resulting in the formation of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.
|
2 | P42800 (/IGI) P42800 (/IGI) |
|
Inositol phosphate metabolic process GO:0043647
The chemical reactions and pathways involving inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
|
2 | Q9NPH2 (/TAS) Q9NPH2 (/TAS) |
|
Mitotic cytokinesis GO:0000281
A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells.
|
1 | Q54N49 (/IMP) |
|
Phospholipid metabolic process GO:0006644
The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester.
|
1 | C8VBX3 (/RCA) |
|
Autophagy GO:0006914
The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.
|
1 | Q54N49 (/IMP) |
|
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
|
1 | Q38862 (/IEP) |
|
Response to high light intensity GO:0009644
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus.
|
1 | Q38862 (/IEP) |
|
Response to auxin GO:0009733
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.
|
1 | Q38862 (/TAS) |
|
Cellular response to phosphate starvation GO:0016036
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of phosphate.
|
1 | Q38862 (/TAS) |
|
Cell-substrate adhesion GO:0031589
The attachment of a cell to the underlying substrate via adhesion molecules.
|
1 | Q54N49 (/IMP) |
|
Response to hydrogen peroxide GO:0042542
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
|
1 | Q38862 (/IEP) |
|
Defense response to bacterium GO:0042742
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
|
1 | Q38862 (/IMP) |
|
Defense response to fungus GO:0050832
Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.
|
1 | Q38862 (/IMP) |
|
Defense response to virus GO:0051607
Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
|
1 | Q38862 (/IMP) |
|
Regulation of phospholipid metabolic process GO:1903725
Any process that modulates the frequency, rate or extent of phospholipid metabolic process.
|
1 | Q54N49 (/IMP) |
There are 7 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
10 | P11986 (/IDA) P11986 (/IDA) P11986 (/IDA) P11986 (/IDA) P11986 (/IDA) P42801 (/IDA) P42801 (/IDA) P42801 (/IDA) Q38862 (/IDA) Q9LX12 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
5 | P11986 (/HDA) P11986 (/HDA) P11986 (/HDA) P11986 (/HDA) P11986 (/HDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | Q9NPH2 (/TAS) Q9NPH2 (/TAS) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
2 | P42800 (/IDA) P42800 (/IDA) |
|
Hyphal cell wall GO:0030446
The cell wall surrounding a fungal hypha.
|
2 | P42800 (/IDA) P42800 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | O97477 (/ISS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q54N49 (/IDA) |
