The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"NAD(P)-binding Rossmann-like Domain
".
FunFam 49: Alanine dehydrogenase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Alanine dehydrogenase activity GO:0000286
Catalysis of the reaction: L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH + H(+).
|
24 |
Q49YD9 (/ISS)
Q49YD9 (/ISS)
Q49YD9 (/ISS)
Q4L750 (/ISS)
Q4L750 (/ISS)
Q4L750 (/ISS)
Q5HNJ6 (/ISS)
Q5HNJ6 (/ISS)
Q5HNJ6 (/ISS)
Q5HNJ6 (/ISS)
(14 more) |
|
Alanine dehydrogenase activity GO:0000286
Catalysis of the reaction: L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH + H(+).
|
15 |
A0QVQ8 (/IDA)
A0QVQ8 (/IDA)
A0QVQ8 (/IDA)
A0QVQ8 (/IDA)
P17556 (/IDA)
P17557 (/IDA)
P9WQB1 (/IDA)
P9WQB1 (/IDA)
P9WQB1 (/IDA)
P9WQB1 (/IDA)
(5 more) |
|
Alanine dehydrogenase activity GO:0000286
Catalysis of the reaction: L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH + H(+).
|
9 | Q08352 (/IMP) Q08352 (/IMP) Q08352 (/IMP) Q08352 (/IMP) Q6LX40 (/IMP) Q8KY18 (/IMP) Q8KY18 (/IMP) Q8KY18 (/IMP) Q8KY18 (/IMP) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Alanine catabolic process GO:0006524
The chemical reactions and pathways resulting in the breakdown of alanine, 2-aminopropanoic acid.
|
31 |
A0QVQ8 (/ISS)
A0QVQ8 (/ISS)
A0QVQ8 (/ISS)
A0QVQ8 (/ISS)
P17556 (/ISS)
P17557 (/ISS)
Q08352 (/ISS)
Q08352 (/ISS)
Q08352 (/ISS)
Q08352 (/ISS)
(21 more) |
|
Alanine metabolic process GO:0006522
The chemical reactions and pathways involving alanine, 2-aminopropanoic acid.
|
8 | Q9KQU3 (/ISS) Q9KQU3 (/ISS) Q9KQU3 (/ISS) Q9KQU3 (/ISS) Q9KQU3 (/ISS) Q9KQU3 (/ISS) Q9KQU3 (/ISS) Q9KQU3 (/ISS) |
|
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
|
5 | P9WQB1 (/IEP) P9WQB1 (/IEP) P9WQB1 (/IEP) P9WQB1 (/IEP) P9WQB1 (/IEP) |
|
Alanine catabolic process GO:0006524
The chemical reactions and pathways resulting in the breakdown of alanine, 2-aminopropanoic acid.
|
5 | P9WQB1 (/IDA) P9WQB1 (/IDA) P9WQB1 (/IDA) P9WQB1 (/IDA) P9WQB1 (/IDA) |
|
Sporulation resulting in formation of a cellular spore GO:0030435
The process in which a relatively unspecialized cell acquires the specialized features of a cellular spore, a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.
|
4 | Q08352 (/IMP) Q08352 (/IMP) Q08352 (/IMP) Q08352 (/IMP) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
27 |
P17556 (/ISS)
P17557 (/ISS)
Q08352 (/ISS)
Q08352 (/ISS)
Q08352 (/ISS)
Q08352 (/ISS)
Q49YD9 (/ISS)
Q49YD9 (/ISS)
Q49YD9 (/ISS)
Q4L750 (/ISS)
(17 more) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
5 | P9WQB1 (/IDA) P9WQB1 (/IDA) P9WQB1 (/IDA) P9WQB1 (/IDA) P9WQB1 (/IDA) |
|
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
|
5 | P9WQB1 (/HDA) P9WQB1 (/HDA) P9WQB1 (/HDA) P9WQB1 (/HDA) P9WQB1 (/HDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
5 | P9WQB1 (/HDA) P9WQB1 (/HDA) P9WQB1 (/HDA) P9WQB1 (/HDA) P9WQB1 (/HDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
5 | P9WQB1 (/HDA) P9WQB1 (/HDA) P9WQB1 (/HDA) P9WQB1 (/HDA) P9WQB1 (/HDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
4 | A0QVQ8 (/IDA) A0QVQ8 (/IDA) A0QVQ8 (/IDA) A0QVQ8 (/IDA) |
