The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 356: Lambda-crystallin homolog

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
L-gulonate 3-dehydrogenase activity GO:0050104
Catalysis of the reaction: L-gulonate + NAD(+) = 3-dehydro-L-gulonate + H(+) + NADH.
7 Q5RDZ2 (/ISS) Q5RDZ2 (/ISS) Q811X6 (/ISS) Q8SPX7 (/ISS) Q8SQ26 (/ISS) Q99KP3 (/ISS) Q99KP3 (/ISS)
NAD+ binding GO:0070403
Interacting selectively and non-covalently with the oxidized form, NAD, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions.
7 Q5RDZ2 (/ISS) Q5RDZ2 (/ISS) Q811X6 (/ISS) Q8SPX7 (/ISS) Q8SQ26 (/ISS) Q99KP3 (/ISS) Q99KP3 (/ISS)
L-gulonate 3-dehydrogenase activity GO:0050104
Catalysis of the reaction: L-gulonate + NAD(+) = 3-dehydro-L-gulonate + H(+) + NADH.
6 P14755 (/IDA) Q9VXI1 (/IDA) Q9Y2S2 (/IDA) Q9Y2S2 (/IDA) Q9Y2S2 (/IDA) Q9Y2S2 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
5 P14755 (/IPI) Q9Y2S2 (/IPI) Q9Y2S2 (/IPI) Q9Y2S2 (/IPI) Q9Y2S2 (/IPI)
NAD+ binding GO:0070403
Interacting selectively and non-covalently with the oxidized form, NAD, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions.
5 P14755 (/IDA) Q9Y2S2 (/IDA) Q9Y2S2 (/IDA) Q9Y2S2 (/IDA) Q9Y2S2 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
2 Q99KP3 (/ISO) Q99KP3 (/ISO)
L-gulonate 3-dehydrogenase activity GO:0050104
Catalysis of the reaction: L-gulonate + NAD(+) = 3-dehydro-L-gulonate + H(+) + NADH.
2 Q99KP3 (/ISO) Q99KP3 (/ISO)
NAD+ binding GO:0070403
Interacting selectively and non-covalently with the oxidized form, NAD, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions.
2 Q99KP3 (/ISO) Q99KP3 (/ISO)
L-gulonate 3-dehydrogenase activity GO:0050104
Catalysis of the reaction: L-gulonate + NAD(+) = 3-dehydro-L-gulonate + H(+) + NADH.
1 Q9VXI1 (/IMP)

There are 1 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glucuronate catabolic process to xylulose 5-phosphate GO:0019640
The chemical reactions and pathways resulting in the breakdown of glucuronate into other compounds, including xylulose 5-phosphate.
4 Q9Y2S2 (/TAS) Q9Y2S2 (/TAS) Q9Y2S2 (/TAS) Q9Y2S2 (/TAS)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
11 Q5RDZ2 (/ISS) Q5RDZ2 (/ISS) Q811X6 (/ISS) Q8SPX7 (/ISS) Q8SQ26 (/ISS) Q99KP3 (/ISS) Q99KP3 (/ISS) Q9Y2S2 (/ISS) Q9Y2S2 (/ISS) Q9Y2S2 (/ISS)
(1 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 Q9Y2S2 (/TAS) Q9Y2S2 (/TAS) Q9Y2S2 (/TAS) Q9Y2S2 (/TAS)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
4 Q9Y2S2 (/HDA) Q9Y2S2 (/HDA) Q9Y2S2 (/HDA) Q9Y2S2 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P14755 (/IDA)
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