The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 35: Adenosylhomocysteinase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
113 A6QLP2 (/IPI) F1MWH2 (/IPI) F1MWH2 (/IPI) F1MWH2 (/IPI) F1MWH2 (/IPI) F1MWH2 (/IPI) F1MWH2 (/IPI) F1MWH2 (/IPI) F1MWH2 (/IPI) F1MWH2 (/IPI)
(103 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
37 O43865 (/IPI) O43865 (/IPI) O43865 (/IPI) O43865 (/IPI) O43865 (/IPI) O43865 (/IPI) O43865 (/IPI) O43865 (/IPI) O43865 (/IPI) O43865 (/IPI)
(27 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
37 Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO)
(27 more)

There are 23 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
MRNA polyadenylation GO:0006378
The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript.
74 O43865 (/IDA) O43865 (/IDA) O43865 (/IDA) O43865 (/IDA) O43865 (/IDA) O43865 (/IDA) O43865 (/IDA) O43865 (/IDA) O43865 (/IDA) O43865 (/IDA)
(64 more)
Regulation of mRNA 3'-end processing GO:0031440
Any process that modulates the frequency, rate or extent of mRNA 3'-end processing, any process involved in forming the mature 3' end of an mRNA molecule.
74 O43865 (/IDA) O43865 (/IDA) O43865 (/IDA) O43865 (/IDA) O43865 (/IDA) O43865 (/IDA) O43865 (/IDA) O43865 (/IDA) O43865 (/IDA) O43865 (/IDA)
(64 more)
Angiotensin-activated signaling pathway GO:0038166
The series of molecular signals generated as a consequence of angiotensin II binding to an angiotensin receptor on the surface of the cell, and proceeding with the activated receptor transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. Ends with regulation of a downstream cellular process, e.g. transcription.
56 B5DFN2 (/ISS) B5DFN2 (/ISS) B5DFN2 (/ISS) B5DFN2 (/ISS) B5DFN2 (/ISS) B5DFN2 (/ISS) B5DFN2 (/ISS) B5DFN2 (/ISS) B5DFN2 (/ISS) B5DFN2 (/ISS)
(46 more)
MRNA polyadenylation GO:0006378
The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript.
37 Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO)
(27 more)
Protein export from nucleus GO:0006611
The directed movement of a protein from the nucleus into the cytoplasm.
37 Q80SW1 (/IDA) Q80SW1 (/IDA) Q80SW1 (/IDA) Q80SW1 (/IDA) Q80SW1 (/IDA) Q80SW1 (/IDA) Q80SW1 (/IDA) Q80SW1 (/IDA) Q80SW1 (/IDA) Q80SW1 (/IDA)
(27 more)
Positive regulation of sodium ion transport GO:0010765
Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
37 Q80SW1 (/IGI) Q80SW1 (/IGI) Q80SW1 (/IGI) Q80SW1 (/IGI) Q80SW1 (/IGI) Q80SW1 (/IGI) Q80SW1 (/IGI) Q80SW1 (/IGI) Q80SW1 (/IGI) Q80SW1 (/IGI)
(27 more)
Positive regulation of sodium ion transport GO:0010765
Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
37 O43865 (/IMP) O43865 (/IMP) O43865 (/IMP) O43865 (/IMP) O43865 (/IMP) O43865 (/IMP) O43865 (/IMP) O43865 (/IMP) O43865 (/IMP) O43865 (/IMP)
(27 more)
Positive regulation of sodium ion transport GO:0010765
Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
37 Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO)
(27 more)
Regulation of mRNA 3'-end processing GO:0031440
Any process that modulates the frequency, rate or extent of mRNA 3'-end processing, any process involved in forming the mature 3' end of an mRNA molecule.
37 Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO)
(27 more)
Regulation of ion transmembrane transporter activity GO:0032412
Any process that modulates the activity of an ion transporter.
37 Q80SW1 (/IGI) Q80SW1 (/IGI) Q80SW1 (/IGI) Q80SW1 (/IGI) Q80SW1 (/IGI) Q80SW1 (/IGI) Q80SW1 (/IGI) Q80SW1 (/IGI) Q80SW1 (/IGI) Q80SW1 (/IGI)
(27 more)
Regulation of ion transmembrane transporter activity GO:0032412
Any process that modulates the activity of an ion transporter.
37 O43865 (/IMP) O43865 (/IMP) O43865 (/IMP) O43865 (/IMP) O43865 (/IMP) O43865 (/IMP) O43865 (/IMP) O43865 (/IMP) O43865 (/IMP) O43865 (/IMP)
(27 more)
Regulation of ion transmembrane transporter activity GO:0032412
Any process that modulates the activity of an ion transporter.
37 Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO)
(27 more)
Angiotensin-activated signaling pathway GO:0038166
The series of molecular signals generated as a consequence of angiotensin II binding to an angiotensin receptor on the surface of the cell, and proceeding with the activated receptor transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. Ends with regulation of a downstream cellular process, e.g. transcription.
37 O43865 (/IDA) O43865 (/IDA) O43865 (/IDA) O43865 (/IDA) O43865 (/IDA) O43865 (/IDA) O43865 (/IDA) O43865 (/IDA) O43865 (/IDA) O43865 (/IDA)
(27 more)
Angiotensin-activated signaling pathway GO:0038166
The series of molecular signals generated as a consequence of angiotensin II binding to an angiotensin receptor on the surface of the cell, and proceeding with the activated receptor transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. Ends with regulation of a downstream cellular process, e.g. transcription.
37 Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO)
(27 more)
Epithelial fluid transport GO:0042045
The directed movement of fluid across epithelia.
37 Q80SW1 (/IDA) Q80SW1 (/IDA) Q80SW1 (/IDA) Q80SW1 (/IDA) Q80SW1 (/IDA) Q80SW1 (/IDA) Q80SW1 (/IDA) Q80SW1 (/IDA) Q80SW1 (/IDA) Q80SW1 (/IDA)
(27 more)
Regulation of anion transport GO:0044070
Any process that modulates the frequency, rate or extent of the directed movement of anions, atoms or small molecules with a net negative charge into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
37 Q80SW1 (/IGI) Q80SW1 (/IGI) Q80SW1 (/IGI) Q80SW1 (/IGI) Q80SW1 (/IGI) Q80SW1 (/IGI) Q80SW1 (/IGI) Q80SW1 (/IGI) Q80SW1 (/IGI) Q80SW1 (/IGI)
(27 more)
Response to calcium ion GO:0051592
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
37 O43865 (/IDA) O43865 (/IDA) O43865 (/IDA) O43865 (/IDA) O43865 (/IDA) O43865 (/IDA) O43865 (/IDA) O43865 (/IDA) O43865 (/IDA) O43865 (/IDA)
(27 more)
Response to calcium ion GO:0051592
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
37 Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO)
(27 more)
Regulation of cardiac conduction GO:1903779
Any process that modulates the frequency, rate or extent of cardiac conduction.
37 O43865 (/TAS) O43865 (/TAS) O43865 (/TAS) O43865 (/TAS) O43865 (/TAS) O43865 (/TAS) O43865 (/TAS) O43865 (/TAS) O43865 (/TAS) O43865 (/TAS)
(27 more)
Dorsal/ventral pattern formation GO:0009953
The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
6 A5PMG3 (/IDA) A5PMG4 (/IDA) B0R047 (/IDA) Q49S41 (/IDA) Q49S42 (/IDA) Q7T2B5 (/IDA)
Dorsal/ventral pattern formation GO:0009953
The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
6 A5PMG3 (/IMP) A5PMG4 (/IMP) B0R047 (/IMP) Q49S41 (/IMP) Q49S42 (/IMP) Q7T2B5 (/IMP)
S-adenosylhomocysteine catabolic process GO:0019510
The chemical reactions and pathways resulting in the breakdown of S-adenosylhomocysteine, forming homocysteine and then methionine.
1 Q9VZX9 (/IMP)
Embryonic morphogenesis GO:0048598
The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants.
1 A5PMG4 (/IMP)

There are 11 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
74 O43865 (/ISS) O43865 (/ISS) O43865 (/ISS) O43865 (/ISS) O43865 (/ISS) O43865 (/ISS) O43865 (/ISS) O43865 (/ISS) O43865 (/ISS) O43865 (/ISS)
(64 more)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
74 O43865 (/ISS) O43865 (/ISS) O43865 (/ISS) O43865 (/ISS) O43865 (/ISS) O43865 (/ISS) O43865 (/ISS) O43865 (/ISS) O43865 (/ISS) O43865 (/ISS)
(64 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
38 Q68FL4 (/IDA) Q80SW1 (/IDA) Q80SW1 (/IDA) Q80SW1 (/IDA) Q80SW1 (/IDA) Q80SW1 (/IDA) Q80SW1 (/IDA) Q80SW1 (/IDA) Q80SW1 (/IDA) Q80SW1 (/IDA)
(28 more)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
38 Q68FL4 (/IDA) Q80SW1 (/IDA) Q80SW1 (/IDA) Q80SW1 (/IDA) Q80SW1 (/IDA) Q80SW1 (/IDA) Q80SW1 (/IDA) Q80SW1 (/IDA) Q80SW1 (/IDA) Q80SW1 (/IDA)
(28 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
37 Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO)
(27 more)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
37 O43865 (/TAS) O43865 (/TAS) O43865 (/TAS) O43865 (/TAS) O43865 (/TAS) O43865 (/TAS) O43865 (/TAS) O43865 (/TAS) O43865 (/TAS) O43865 (/TAS)
(27 more)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
37 Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO) Q80SW1 (/ISO)
(27 more)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
37 O43865 (/HDA) O43865 (/HDA) O43865 (/HDA) O43865 (/HDA) O43865 (/HDA) O43865 (/HDA) O43865 (/HDA) O43865 (/HDA) O43865 (/HDA) O43865 (/HDA)
(27 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
19 B5DFN2 (/IDA) B5DFN2 (/IDA) B5DFN2 (/IDA) B5DFN2 (/IDA) B5DFN2 (/IDA) B5DFN2 (/IDA) B5DFN2 (/IDA) B5DFN2 (/IDA) B5DFN2 (/IDA) B5DFN2 (/IDA)
(9 more)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
19 B5DFN2 (/IDA) B5DFN2 (/IDA) B5DFN2 (/IDA) B5DFN2 (/IDA) B5DFN2 (/IDA) B5DFN2 (/IDA) B5DFN2 (/IDA) B5DFN2 (/IDA) B5DFN2 (/IDA) B5DFN2 (/IDA)
(9 more)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
1 Q68FL4 (/IDA)
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