The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"NAD(P)-binding Rossmann-like Domain
".
FunFam 246: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
NADH dehydrogenase activity GO:0003954
Catalysis of the reaction: NADH + H+ + acceptor = NAD+ + reduced acceptor.
|
1 | Q16795 (/IMP) |
NADH dehydrogenase activity GO:0003954
Catalysis of the reaction: NADH + H+ + acceptor = NAD+ + reduced acceptor.
|
1 | Q9DC69 (/ISO) |
NADH dehydrogenase activity GO:0003954
Catalysis of the reaction: NADH + H+ + acceptor = NAD+ + reduced acceptor.
|
1 | Q16795 (/NAS) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q16795 (/IPI) |
NADH dehydrogenase (ubiquinone) activity GO:0008137
Catalysis of the reaction: NADH + ubiquinone + 5 H(+)(in) <=> NAD(+) + ubiquinol + 4 H(+)(out).
|
1 | Q16795 (/NAS) |
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
|
1 | Q16795 (/IDA) |
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
|
1 | Q9DC69 (/ISO) |
There are 12 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Mitochondrial respiratory chain complex I assembly GO:0032981
The aggregation, arrangement and bonding together of a set of components to form mitochondrial respiratory chain complex I.
|
13 |
P0CB81 (/ISS)
P0CB81 (/ISS)
P0CB81 (/ISS)
P0CB82 (/ISS)
P0CB82 (/ISS)
P0CB82 (/ISS)
P34943 (/ISS)
Q0MQB3 (/ISS)
Q0MQB4 (/ISS)
Q0MQB4 (/ISS)
(3 more) |
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
|
11 |
P0CB81 (/ISS)
P0CB81 (/ISS)
P0CB81 (/ISS)
P0CB82 (/ISS)
P0CB82 (/ISS)
P0CB82 (/ISS)
Q0MQB4 (/ISS)
Q0MQB4 (/ISS)
Q0MQB4 (/ISS)
Q5BK63 (/ISS)
(1 more) |
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
|
5 | A7MCD7 (/IDA) A8E515 (/IDA) F6NP87 (/IDA) Q5BJB8 (/IDA) Q6NUY8 (/IDA) |
Mitochondrial electron transport, NADH to ubiquinone GO:0006120
The transfer of electrons from NADH to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex I.
|
1 | Q16795 (/NAS) |
Mitochondrial electron transport, NADH to ubiquinone GO:0006120
The transfer of electrons from NADH to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex I.
|
1 | Q16795 (/TAS) |
Sodium ion transport GO:0006814
The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q16795 (/NAS) |
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
|
1 | Q16795 (/IDA) |
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
|
1 | Q9DC69 (/ISO) |
Response to glucose GO:0009749
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
|
1 | Q5BK63 (/IEP) |
Mitochondrial respiratory chain complex I assembly GO:0032981
The aggregation, arrangement and bonding together of a set of components to form mitochondrial respiratory chain complex I.
|
1 | Q16795 (/IMP) |
Mitochondrial respiratory chain complex I assembly GO:0032981
The aggregation, arrangement and bonding together of a set of components to form mitochondrial respiratory chain complex I.
|
1 | Q9DC69 (/ISO) |
Mitochondrial respiratory chain complex I assembly GO:0032981
The aggregation, arrangement and bonding together of a set of components to form mitochondrial respiratory chain complex I.
|
1 | Q16795 (/TAS) |
There are 15 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Mitochondrial respiratory chain complex I GO:0005747
A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
|
11 |
P0CB81 (/ISS)
P0CB81 (/ISS)
P0CB81 (/ISS)
P0CB82 (/ISS)
P0CB82 (/ISS)
P0CB82 (/ISS)
Q0MQB3 (/ISS)
Q0MQB4 (/ISS)
Q0MQB4 (/ISS)
Q0MQB4 (/ISS)
(1 more) |
Mitochondrial respiratory chain complex I GO:0005747
A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
|
3 | P34943 (/IDA) Q16795 (/IDA) Q9DC69 (/IDA) |
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | Q16795 (/IDA) Q5BK63 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q16795 (/HDA) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q16795 (/IDA) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q9DC69 (/ISO) |
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | Q9DC69 (/HDA) |
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | Q9DC69 (/ISO) |
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
|
1 | Q9DC69 (/HDA) |
Mitochondrial respiratory chain complex I GO:0005747
A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
|
1 | Q9DC69 (/ISO) |
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
|
1 | Q16795 (/IDA) |
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
|
1 | Q9DC69 (/ISO) |
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
|
1 | Q16795 (/TAS) |
Mitochondrial membrane GO:0031966
Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.
|
1 | Q16795 (/IDA) |
Mitochondrial membrane GO:0031966
Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.
|
1 | Q9DC69 (/ISO) |