The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"NAD(P)-binding Rossmann-like Domain
".
FunFam 195: Glyoxylate reductase/hydroxypyruvate reductase b
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 18 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Glycerate dehydrogenase activity GO:0008465
Catalysis of the reaction: (R)-glycerate + NAD+ = hydroxypyruvate + NADH + H+.
|
3 | B0BN46 (/IDA) Q9UBQ7 (/IDA) Q9UBQ7 (/IDA) |
|
Hydroxypyruvate reductase activity GO:0016618
Catalysis of the reaction: D-glycerate + NADP+ = hydroxypyruvate + NADPH + H+.
|
3 | B0BN46 (/IDA) Q9UBQ7 (/IDA) Q9UBQ7 (/IDA) |
|
Glyoxylate reductase (NADP) activity GO:0030267
Catalysis of the reaction: glycolate + NADP+ = glyoxylate + NADPH + H+.
|
3 | B0BN46 (/IDA) Q9UBQ7 (/IDA) Q9UBQ7 (/IDA) |
|
Glycerate dehydrogenase activity GO:0008465
Catalysis of the reaction: (R)-glycerate + NAD+ = hydroxypyruvate + NADH + H+.
|
2 | Q91Z53 (/ISO) Q91Z53 (/ISO) |
|
Hydroxypyruvate reductase activity GO:0016618
Catalysis of the reaction: D-glycerate + NADP+ = hydroxypyruvate + NADPH + H+.
|
2 | Q91Z53 (/ISO) Q91Z53 (/ISO) |
|
Glyoxylate reductase (NADP) activity GO:0030267
Catalysis of the reaction: glycolate + NADP+ = glyoxylate + NADPH + H+.
|
2 | Q91Z53 (/ISO) Q91Z53 (/ISO) |
|
Glyoxylate reductase (NADP) activity GO:0030267
Catalysis of the reaction: glycolate + NADP+ = glyoxylate + NADPH + H+.
|
2 | Q9UBQ7 (/TAS) Q9UBQ7 (/TAS) |
|
Carboxylic acid binding GO:0031406
Interacting selectively and non-covalently with a carboxylic acid, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).
|
2 | Q91Z53 (/ISO) Q91Z53 (/ISO) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
2 | Q9UBQ7 (/IDA) Q9UBQ7 (/IDA) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
2 | Q91Z53 (/ISO) Q91Z53 (/ISO) |
|
NADP binding GO:0050661
Interacting selectively and non-covalently with nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH.
|
2 | Q91Z53 (/ISO) Q91Z53 (/ISO) |
|
NAD binding GO:0051287
Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.
|
2 | Q91Z53 (/ISO) Q91Z53 (/ISO) |
|
NAD binding GO:0051287
Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.
|
2 | Q9UBQ7 (/TAS) Q9UBQ7 (/TAS) |
|
NADPH binding GO:0070402
Interacting selectively and non-covalently with the reduced form, NADPH, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.
|
2 | Q9UBQ7 (/IDA) Q9UBQ7 (/IDA) |
|
NADPH binding GO:0070402
Interacting selectively and non-covalently with the reduced form, NADPH, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.
|
2 | Q91Z53 (/ISO) Q91Z53 (/ISO) |
|
Carboxylic acid binding GO:0031406
Interacting selectively and non-covalently with a carboxylic acid, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).
|
1 | B0BN46 (/IPI) |
|
NADP binding GO:0050661
Interacting selectively and non-covalently with nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH.
|
1 | B0BN46 (/IDA) |
|
NAD binding GO:0051287
Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.
|
1 | B0BN46 (/IDA) |
There are 11 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Excretion GO:0007588
The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.
|
2 | Q9UBQ7 (/IMP) Q9UBQ7 (/IMP) |
|
Excretion GO:0007588
The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.
|
2 | Q91Z53 (/ISO) Q91Z53 (/ISO) |
|
Cellular nitrogen compound metabolic process GO:0034641
The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.
|
2 | Q9UBQ7 (/TAS) Q9UBQ7 (/TAS) |
|
Dicarboxylic acid metabolic process GO:0043648
The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-).
|
2 | Q91Z53 (/ISO) Q91Z53 (/ISO) |
|
Glyoxylate metabolic process GO:0046487
The chemical reactions and pathways involving glyoxylate, the anion of glyoxylic acid, HOC-COOH.
|
2 | Q9UBQ7 (/IDA) Q9UBQ7 (/IDA) |
|
Glyoxylate metabolic process GO:0046487
The chemical reactions and pathways involving glyoxylate, the anion of glyoxylic acid, HOC-COOH.
|
2 | Q91Z53 (/ISO) Q91Z53 (/ISO) |
|
Protein complex oligomerization GO:0051259
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
|
2 | Q9UBQ7 (/IDA) Q9UBQ7 (/IDA) |
|
Protein complex oligomerization GO:0051259
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
|
2 | Q91Z53 (/ISO) Q91Z53 (/ISO) |
|
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
|
2 | Q9UBQ7 (/IDA) Q9UBQ7 (/IDA) |
|
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
|
2 | Q91Z53 (/ISO) Q91Z53 (/ISO) |
|
Dicarboxylic acid metabolic process GO:0043648
The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-).
|
1 | B0BN46 (/IDA) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q9UBQ7 (/IDA) Q9UBQ7 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q91Z53 (/ISO) Q91Z53 (/ISO) |
|
Peroxisomal matrix GO:0005782
The volume contained within the membranes of a peroxisome; in many cells the matrix contains a crystalloid core largely composed of urate oxidase.
|
2 | Q9UBQ7 (/TAS) Q9UBQ7 (/TAS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | Q91Z53 (/ISO) Q91Z53 (/ISO) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
2 | Q9UBQ7 (/HDA) Q9UBQ7 (/HDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | B0BN46 (/IDA) |
