The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"NAD(P)-binding Rossmann-like Domain
".
FunFam 165: 3-ketodihydrosphingosine reductase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
3-dehydrosphinganine reductase activity GO:0047560
Catalysis of the reaction: NADP(+) + sphinganine = 3-dehydrosphinganine + H(+) + NADPH.
|
6 | F4JZN6 (/IDA) Q06136 (/IDA) Q06136 (/IDA) Q06136 (/IDA) Q06136 (/IDA) Q0WRJ2 (/IDA) |
|
3-dehydrosphinganine reductase activity GO:0047560
Catalysis of the reaction: NADP(+) + sphinganine = 3-dehydrosphinganine + H(+) + NADPH.
|
4 | Q06136 (/IMP) Q06136 (/IMP) Q06136 (/IMP) Q06136 (/IMP) |
|
3-dehydrosphinganine reductase activity GO:0047560
Catalysis of the reaction: NADP(+) + sphinganine = 3-dehydrosphinganine + H(+) + NADPH.
|
4 | Q06136 (/TAS) Q06136 (/TAS) Q06136 (/TAS) Q06136 (/TAS) |
|
3-dehydrosphinganine reductase activity GO:0047560
Catalysis of the reaction: NADP(+) + sphinganine = 3-dehydrosphinganine + H(+) + NADPH.
|
2 | Q6GV12 (/ISO) Q6GV12 (/ISO) |
|
3-dehydrosphinganine reductase activity GO:0047560
Catalysis of the reaction: NADP(+) + sphinganine = 3-dehydrosphinganine + H(+) + NADPH.
|
1 | Q9VBU5 (/ISS) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
3-keto-sphinganine metabolic process GO:0006666
The chemical reactions and pathways involving 3-keto-sphinganine, a derivative of sphinganine with a ketone group at C3. It is an intermediate in the synthesis of sphingosine.
|
4 | Q06136 (/IDA) Q06136 (/IDA) Q06136 (/IDA) Q06136 (/IDA) |
|
Sphingolipid biosynthetic process GO:0030148
The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
|
4 | Q06136 (/TAS) Q06136 (/TAS) Q06136 (/TAS) Q06136 (/TAS) |
|
3-keto-sphinganine metabolic process GO:0006666
The chemical reactions and pathways involving 3-keto-sphinganine, a derivative of sphinganine with a ketone group at C3. It is an intermediate in the synthesis of sphingosine.
|
2 | Q6GV12 (/ISO) Q6GV12 (/ISO) |
|
Sphingolipid biosynthetic process GO:0030148
The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
|
2 | Q6GV12 (/IGI) Q6GV12 (/IGI) |
|
Sphingolipid biosynthetic process GO:0030148
The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
|
2 | F4JZN6 (/IMP) Q0WRJ2 (/IMP) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
4 | Q06136 (/TAS) Q06136 (/TAS) Q06136 (/TAS) Q06136 (/TAS) |
|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
4 | Q06136 (/IDA) Q06136 (/IDA) Q06136 (/IDA) Q06136 (/IDA) |
|
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
|
4 | Q06136 (/TAS) Q06136 (/TAS) Q06136 (/TAS) Q06136 (/TAS) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
4 | Q06136 (/HDA) Q06136 (/HDA) Q06136 (/HDA) Q06136 (/HDA) |
|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
2 | Q6GV12 (/ISO) Q6GV12 (/ISO) |
|
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
|
2 | F4JZN6 (/IDA) Q0WRJ2 (/IDA) |
