The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
HUPs
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 463: Cytoplasmic tRNA 2-thiolation protein 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
TRNA binding GO:0000049
Interacting selectively and non-covalently with transfer RNA.
1 O94282 (/IPI)
TRNA binding GO:0000049
Interacting selectively and non-covalently with transfer RNA.
1 O94282 (/ISS)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 O94282 (/ISM)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
TRNA wobble uridine modification GO:0002098
The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified.
1 O94282 (/ISS)
TRNA wobble position uridine thiolation GO:0002143
The process in which a uridine residue at position 34 in the anticodon of a tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps.
1 O94282 (/IMP)
TRNA thio-modification GO:0034227
The addition a sulfur atom to a nucleotide in a tRNA molecule.
1 O94282 (/ISS)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosolic tRNA wobble base thiouridylase complex GO:0002144
A complex of two proteins involved in the thiolation of U34 in glutamate, lysine, and glutamine tRNAs of eukaryotes.
1 O94282 (/IPI)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O94282 (/ISS)
CATH-Gene3D is a Global Biodata Core Resource Learn more...