The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"HUPs
".
FunFam 151: Phosphoadenosine phosphosulfate reductase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phosphoadenylyl-sulfate reductase (thioredoxin) activity GO:0004604
Catalysis of the reaction: adenosine 3',5'-diphosphate + H(+) + sulfite + thioredoxin disulfide = 3'-phospho-5'-adenylyl sulfate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin; 3'-phosphoadenosine 5'-phosphosulfate is also known as PAPS.
|
9 | P18408 (/IMP) P18408 (/IMP) P18408 (/IMP) P18408 (/IMP) P18408 (/IMP) P18408 (/IMP) P18408 (/IMP) P18408 (/IMP) P56859 (/IMP) |
|
Phosphoadenylyl-sulfate reductase (thioredoxin) activity GO:0004604
Catalysis of the reaction: adenosine 3',5'-diphosphate + H(+) + sulfite + thioredoxin disulfide = 3'-phospho-5'-adenylyl sulfate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin; 3'-phosphoadenosine 5'-phosphosulfate is also known as PAPS.
|
8 | P18408 (/IDA) P18408 (/IDA) P18408 (/IDA) P18408 (/IDA) P18408 (/IDA) P18408 (/IDA) P18408 (/IDA) P18408 (/IDA) |
|
3'-Phosphoadenylylselenate reductase activity GO:0098624
Catalysis of the reaction: 3'-Phosphoadenylylselenate + NADPH => Adenosine 3',5'-bisphosphate + Selenite + NADP+ + H+.
|
8 | P18408 (/TAS) P18408 (/TAS) P18408 (/TAS) P18408 (/TAS) P18408 (/TAS) P18408 (/TAS) P18408 (/TAS) P18408 (/TAS) |
|
Phosphoadenylyl-sulfate reductase (thioredoxin) activity GO:0004604
Catalysis of the reaction: adenosine 3',5'-diphosphate + H(+) + sulfite + thioredoxin disulfide = 3'-phospho-5'-adenylyl sulfate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin; 3'-phosphoadenosine 5'-phosphosulfate is also known as PAPS.
|
1 | P56859 (/ISA) |
|
Phosphoadenylyl-sulfate reductase (thioredoxin) activity GO:0004604
Catalysis of the reaction: adenosine 3',5'-diphosphate + H(+) + sulfite + thioredoxin disulfide = 3'-phospho-5'-adenylyl sulfate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin; 3'-phosphoadenosine 5'-phosphosulfate is also known as PAPS.
|
1 | Q10270 (/ISO) |
|
Phosphoadenylyl-sulfate reductase (thioredoxin) activity GO:0004604
Catalysis of the reaction: adenosine 3',5'-diphosphate + H(+) + sulfite + thioredoxin disulfide = 3'-phospho-5'-adenylyl sulfate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin; 3'-phosphoadenosine 5'-phosphosulfate is also known as PAPS.
|
1 | P56859 (/RCA) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Glutathione biosynthetic process GO:0006750
The chemical reactions and pathways resulting in the formation of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins.
|
8 | P18408 (/IMP) P18408 (/IMP) P18408 (/IMP) P18408 (/IMP) P18408 (/IMP) P18408 (/IMP) P18408 (/IMP) P18408 (/IMP) |
|
Sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) GO:0019379
The pathway by which inorganic sulfate is processed and incorporated into sulfated compounds, where the phosphoadenylyl sulfate reduction step is catalyzed by the enzyme phosphoadenylyl-sulfate reductase (thioredoxin) (EC:1.8.4.8).
|
8 | P18408 (/IDA) P18408 (/IDA) P18408 (/IDA) P18408 (/IDA) P18408 (/IDA) P18408 (/IDA) P18408 (/IDA) P18408 (/IDA) |
|
Sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) GO:0019379
The pathway by which inorganic sulfate is processed and incorporated into sulfated compounds, where the phosphoadenylyl sulfate reduction step is catalyzed by the enzyme phosphoadenylyl-sulfate reductase (thioredoxin) (EC:1.8.4.8).
|
8 | P18408 (/IMP) P18408 (/IMP) P18408 (/IMP) P18408 (/IMP) P18408 (/IMP) P18408 (/IMP) P18408 (/IMP) P18408 (/IMP) |
|
Cellular response to drug GO:0035690
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
|
2 | Q5A0Z0 (/IMP) Q5A0Z0 (/IMP) |
|
Sulfate assimilation GO:0000103
The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.
|
1 | P56859 (/IMP) |
|
Cysteine metabolic process GO:0006534
The chemical reactions and pathways involving cysteine, 2-amino-3-mercaptopropanoic acid.
|
1 | P56859 (/RCA) |
|
Sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) GO:0019379
The pathway by which inorganic sulfate is processed and incorporated into sulfated compounds, where the phosphoadenylyl sulfate reduction step is catalyzed by the enzyme phosphoadenylyl-sulfate reductase (thioredoxin) (EC:1.8.4.8).
|
1 | Q10270 (/ISO) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
8 | P18408 (/IC) P18408 (/IC) P18408 (/IC) P18408 (/IC) P18408 (/IC) P18408 (/IC) P18408 (/IC) P18408 (/IC) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
8 | P18408 (/TAS) P18408 (/TAS) P18408 (/TAS) P18408 (/TAS) P18408 (/TAS) P18408 (/TAS) P18408 (/TAS) P18408 (/TAS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q10270 (/HDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q10270 (/HDA) |
